1974
DOI: 10.1016/s0140-6736(74)92340-x
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ALGINATE/ANTACID IN THE REDUCTION OF GASTRO-$OElig;SOPHAGEAL REFLUX

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Cited by 122 publications
(29 citation statements)
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“…Antacids (60) and alginic acid (61,62) have been shown to be more effective than placebo in the relief of symptoms induced by a heartburn promoting meal. In addition, combined antacid/alginic acid therapy may be superior to antacids alone in the control of symptoms (63,64). There are two long-term trials, which suggest effective symptom relief in approximately 20% of patients using OTC agents (65,66).…”
Section: Level Of Evidence: IVmentioning
confidence: 99%
“…Antacids (60) and alginic acid (61,62) have been shown to be more effective than placebo in the relief of symptoms induced by a heartburn promoting meal. In addition, combined antacid/alginic acid therapy may be superior to antacids alone in the control of symptoms (63,64). There are two long-term trials, which suggest effective symptom relief in approximately 20% of patients using OTC agents (65,66).…”
Section: Level Of Evidence: IVmentioning
confidence: 99%
“…Antacids (51) and alginic acid (52,53) have been shown to be more effective than placebo in the relief of symptoms induced by a heartburn-promoting meal. In addition, combined antacid/ alginic acid therapy may be superior to antacids alone in the control of symptoms (54,55). There are two long-term trials that suggest effective symptom relief in approximately 20% of patients using over-the-counter agents (56,57).…”
Section: No Change Lifestyle Modification Should Be Initiated and Conmentioning
confidence: 99%
“…These drugs are effective in the treatment of esophagitis and relief of heartburn. The presence of simethicone, dimethicone, or alginates may be additionally protective [36,37]. The usual dose of aluminum and magnesium compounds is 30 to 60 ml/1.73 m 2 /day.…”
Section: Therapeutic Methodsmentioning
confidence: 99%