Algae-derived β-glucan enhanced gut health and immune responses of weaned pigs experimentally infected with a pathogenic E. coli

Dietary supplementation of Bacillus subtilis influenced intestinal health of weaned pigs experimentally infected with a pathogenic E. coli

“…In the present study, pigs in E. coli challenge groups had increased frequency of diarrhea and β-hemolytic coliforms in their feces, reduced intestinal villi, and increased gut permeability after F18 E. coli infection, compared with pigs in the negative control group. These observations are consistent with previously published research using the same E. coli strain [18][19][20]30]. The clear clinical signs and symptoms indicated the pigs were successfully infected with F18 E. coli.…”

Proceedings of the Seventeenth Biennial Conference of the Australasian Pig Science Association (APSA)

“…Indigestible oligo-and disaccharides from fungal fermentation of feed material can bind and reduce intestinal pathogens such as Salmonella typhimurium or E.coli and exhibit a prebiotic effect (Agunos et al, 2007). In addition, fungal cell wall components including beta-glucans may reveal prebiotic properties supporting intestinal health (Kim et al, 2019). Organic acids are known to increase stomach barrier function by reducing stomach pH and destabilize bacterial membrane function resulting in bacterial cell death (Zentek et al, 2013).…”

“…This could result in more cost-effective diets without losing on performance. Previous studies on nutritional emulsifiers focused on the application of mixtures containing glycerol polyethylene glycol ricinolate (GPGR) (Sun and Kim, 2019), which showed that GPGR is an agent that can be used to improve emulsification of fats in swine. In this study, it is hypothesised that GPGR as such, can also have a significant impact on the performance of swine and in particular in energy reduced diets.…”

Pathogenicity and Competitive Fitness of Salmonella enterica Serovar 4,[5],12:i:- Compared to Salmonella Typhimurium and Salmonella Derby in Swine

“…However, that study utilized fecal moisture content to determine if the pigs had developed diarrhea (21). Fecal moisture content analysis is a much more objective way to evaluate the level of diarrhea in swine compared to fecal scoring, even though fecal scoring is a more common method in studies of this type (41,50). Due to the size and scope of our study, we utilized fecal scoring to facilitate evaluation of a larger sample size.…”