from "0" (awake, agitated) to "6" (asleep, non-responsive . Times to awakening were longer in Group H: 3.1 • 3.4 hr, than in Group L' L1 • 0.8 h, P < 0.05. Pharmacokinetic variables were found to be dose-independent over the range of infusion rates. Mean values were tt/2 [J = 4.4 • L5 hr, provides