Alfentanil Causes Less Postoperative Nausea and Vomiting than Equipotent Doses of Fentanyl or Sufentanil in Outpatients 

Abstract

Alfentanil, compared with approximately equipotent doses of fentanyl and sufentanil, is associated with a lower incidence of postoperative nausea and vomiting in outpatients.

The impact of isoflurane, desflurane, or sevoflurane on the frequency and severity of postoperative nausea and vomiting after lumbar disc surgery

“…Furthermore, different pharmacological traits such as solubility in blood, lean tissue and fat, metabolic transformation and elimination (reduced hepatic metabolism of concomitant medications, amount of fluoride ions), or different effects on stress hormone changes [11], may be responsible for different side effects and complications such as PONV. Whatever the nature of the inhalation anesthetic used, the incidence and severity of PONV are influenced by risk factors such as female gender, nonsmoker status, and history of PONV [12,13]; by the type of surgery [14,15]; and by the opioid and antiemetic drugs used in the perioperative course of anesthesia [16,17].…”

Dexamethasone, Metoclopramide, and Their Combination for the Prevention of Postoperative Nausea and Vomiting in Female Patients With Moderate-to-High Risk for Ponv Undergoing Laparoscopic Surgery

“…Our results are congruent with a previous study. [16] The recommended dose for Metoclopramide is 10 mg IV. [9] However, Metoclopramide is not effective in reducing PONV at a 10 mg dosage.…”

The potential for μ‐opioid receptor agonists to be anti‐emetic in humans: a review of clinical data

“…53 Older studies looking for differences between individual non-remifentanil phenylpiperidine derivatives have been contradictory. Brown et al 54 reported no significant differences between alfentanil and fentanyl used intra-operatively for pelvic laparoscopy, whereas Langevin et al 55 reported that the use of alfentanil on induction was associated with less PONV compared with both fentanyl and sufentanil.…”