1993
DOI: 10.1097/00008506-199301000-00005
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Alfentanil Administered Prior to Endotracheal Suctioning Reduces Cerebral Perfusion Pressure

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Cited by 18 publications
(15 citation statements)
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“…Hanowell et al (1993) studied the effect of alfentanil (an opiate) given prior to ETS on the ICP and CPP of six head‐injured adults. This quasi‐experimental study compared the administration of saline, 15 and 30 μg/kg of alfentanil prior to ETS.…”
Section: Resultsmentioning
confidence: 99%
“…Hanowell et al (1993) studied the effect of alfentanil (an opiate) given prior to ETS on the ICP and CPP of six head‐injured adults. This quasi‐experimental study compared the administration of saline, 15 and 30 μg/kg of alfentanil prior to ETS.…”
Section: Resultsmentioning
confidence: 99%
“…*P < 0.05 versus T0. 32 Patients receiving neuromuscular blockers were not included to ensure that sedation was optimal (absence of any movement during ETS, bispectral index <50). aerosolizers that synchronize to the initial inspiratory phase should further improve the tracheobronchial delivery of lidocaine.…”
Section: Discussionmentioning
confidence: 99%
“…One RCT (93) and four randomized crossover trials (94)(95)(96)(97) were designed to assess the effectiveness of a variety of pharmacological agents on ICP and CPP in patients with acute head injury. The studies included patients who had severe brain injury with decreased levels of consciousness requiring ventilatory support.…”
Section: Practice Guidelines For Suctioningmentioning
confidence: 99%
“…The studies included patients who had severe brain injury with decreased levels of consciousness requiring ventilatory support. The interventions assessed were neuromuscular blocking agents (93,94), topical and parenteral anesthetic agents (94)(95)(96), barbiturates (94) and narcotics (94,97). One study assessed the effect of hyperventilation as a co-intervention (96).…”
Section: Practice Guidelines For Suctioningmentioning
confidence: 99%
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