Aleutian Disease in Two Domestic Striped Skunks (<i>Mephitis mephitis</i>)

Pennick, Kate E.; Latimer, Kenneth S.; Brown, Cathy A.; Hayes, Jeff; Sarver, C. F.

doi:10.1354/vp.44-5-687

Cited by 22 publications

(24 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Reports describing pathologic findings in skunks with AD are limited to 3 cases diagnosed in captive/pet individuals in Tennessee, Georgia, and Ohio. 2,8 All referenced cases described multisystemic plasmacytic and lymphocytic inflammation, as seen in the present cases. Encephalomalacia associated with cerebral microangiopathy has not been previously described in skunks with AD.…”

supporting

confidence: 62%

“…6 ADV infection in mink causes infiltration of plasma cells in multiple tissues, hypergammaglobulinemia, glomerulonephritis, arteritis, splenomegaly, hepatitis, meningoencephalitis, and death. 6,9 Despite documented ADV infection and disease in captive striped skunks, 2,8 as well as serologic evidence of infection with a related virus in wild striped skunks, 3 little is known about the pathogenicity of the virus in skunks or the relevance of infection in free-ranging animals. 9 This study describes lesions in 7 free-ranging striped skunks with AD and their temporospatial distribution.…”

mentioning

confidence: 99%

“…4 and 6 were processed for detection of ADV nucleic acid by in situ hybridization (ISH) using a commercially available DNA probe (Roche Applied Science, Indianapolis, IN) based on the referenced protocol. 8 Fresh-frozen samples of kidney, as well as either pooled or individual samples of liver, lung, spleen, brain, and/or urine, from case Nos. 1 to 5 and 7 were submitted to either the Wisconsin Veterinary Diagnostic Laboratory (University of Wisconsin, Madison, WI; case Nos.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Aleutian Disease

et al. 2014

View full text Add to dashboard Cite

Aleutian disease virus (ADV, Amdovirus, Parvoviridae) primarily infects farmed mustelids (mink and ferrets) but also other fur-bearing animals and humans. Three Aleutian disease (AD) cases have been described in captive striped skunks; however, little is known about the relevance of AD in free-ranging carnivores. This work describes the pathological findings and temporospatial distribution in 7 cases of AD in free-ranging striped skunks. All cases showed neurologic disease and were found in a 46-month period (2010-2013) within a localized geographical region in California. Lesions included multisystemic plasmacytic and lymphocytic inflammation (ie, interstitial nephritis, myocarditis, hepatitis, meningoencephalitis, pneumonia, and splenitis), glomerulonephritis, arteritis with or without fibrinoid necrosis in several organs (ie, kidney, heart, brain, and spleen), splenomegaly, ascites/hydrothorax, and/or encephalomalacia with cerebral microangiopathy. ADV infection was confirmed in all cases by specific polymerase chain reaction and/or in situ hybridization. The results suggest that AD is an emerging disease in free-ranging striped skunks in California.

show abstract

supporting

confidence: 62%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Aleutian Disease

et al. 2014

View full text Add to dashboard Cite

show abstract

“…The occurrence of natural infection with or exposure to AMDV in a few members of the Mustelidae family (e.g., European mink, ferrets, polecats, stone martens, pine martens, Eurasian otters), and other carnivores (striped skunks, common genets, raccoons, foxes) has also been reported [6,8,[10][11][12][13][14]. Information on the prevalence of AMDV in wildlife in Eastern Canada is limited to one report on the feral American mink [3].…”

Section: Introductionmentioning

confidence: 99%

Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada

Farid¹

2012

Proceedings of the XTH International Scientific Congress in Fur Animal Production

View full text Add to dashboard Cite

Background: Aleutian mink disease virus (AMDV) is widespread among ranched and free-ranging American mink in Canada, but there is no information on its prevalence in other wild animal species. This paper describes the prevalence of AMDV of 12 furbearing species in Nova Scotia (NS), Canada. Methods: Samples were collected from carcasses of 462 wild animals of 12 furbearing species, trapped in 10 NS counties between November 2009 and February 2011. Viral DNA was tested by PCR using two primer pairs, and anti-viral antibodies were tested by counterimmunoelectrophoresis (CIEP) on spleen homogenates. Results: Positive PCR or CIEP samples were detected in 56 of 60 (93.3%) American mink, 43 of 61 (70.5%) short-tailed weasels, 2 of 8 (25.0%) striped skunks, 2 of 11 (18.2%) North American river otters, 9 of 85 (10.6%) raccoons, and 2 of 20 (10.0%) bobcats. Samples from six fishers, 24 coyotes, 25 red foxes, 58 beavers, 45 red-squirrels and 59 muskrats were negative. Antibodies to AMDV were detected by CIEP in 16 of 56 (28.6%) mink and one of the 8 skunks (12.5%). Thirteen of the mink were positive for PCR and CIEP, but three mink and one skunk were CIEP positive and PCR negative. Positive CIEP or PCR animals were present in all nine counties from which mink or weasel samples were collected. Conclusions:The presence of AMDV in so many species across the province has important epidemiological ramifications and could pose a serious health problem for the captive mink, as well as for susceptible wildlife. The mechanism of virus transmission between wildlife and captive mink and the effects of AMDV exposure on the viability of the susceptible species deserve further investigation.

show abstract

“…Wildlife other than American mink can become infected with or exposed to AMDV, including striped skunk (Mephitis mephitis), ermine (Mustela erminea), European mink (Mustela lutreola), raccoon dog (Nyctereutes procyonoides), and raccoon (Procyon lotor) (Alexandersen et al 1985;Mañ as et al 2001;Pennick et al 2007;Farid 2013). Given demonstrated global problems with mink farm biosecurity (Bonesi and Palazon 2007;Bowman et al 2007), there is potential for mink farms to be sources of cross-species spillover of AMDV (Nituch et al 2011(Nituch et al , 2012.…”

mentioning

confidence: 99%

Testing for Aleutian Mink Disease Virus in the River Otter (Lontra canadensis) in Sympatry with Infected American Mink (Neovison vison)

Bowman

Kidd

Nituch

et al. 2014

Journal of Wildlife Diseases

View full text Add to dashboard Cite

ABSTRACT:Aleutian mink disease virus (AMDV) occurs in the American mink (Neovison vison) in wild populations and on mink farms and can cause illness and death. The North American river otter (Lontra canadensis) may be exposed to AMDV because of shared space and habitat with mink. Using serology and real-time PCR, we tested river otters across Ontario for AMDV infection. We found no evidence of infection in otters, a surprising finding given the sympatric distribution, niche overlap, and close phylogenetic relationship of the river otter and the American mink. Our results are consistent with the hypothesis that the major point of spillover of AMDV between mink farms and wildlife is manure and composting carcasses on mink farms. Mink farms in Ontario are generally in agricultural landscapes; it is unlikely that river otter use these habitats and thus are likely not exposed to AMDV. We found no evidence that AMD is an important disease for the river otters in Ontario.

show abstract

Aleutian Disease in Two Domestic Striped Skunks (Mephitis mephitis)

Cited by 22 publications

References 7 publications

Aleutian Disease

Aleutian Disease

Aleutian mink disease virus in furbearing mammals in Nova Scotia, Canada

Testing for Aleutian Mink Disease Virus in the River Otter (Lontra canadensis) in Sympatry with Infected American Mink (Neovison vison)

Contact Info

Product

Resources

About