Alergólogica 2015: A National Survey on Allergic Diseases in the Spanish Pediatric Population

Ojeda, Pedro; Ibáñez, María Dolores; Olaguíbel, J M; Sastre, Joaquı́n; Chivato, T.

doi:10.18176/jiaci.0308

Cited by 28 publications

(25 citation statements)

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“…Finally, a high proportion of asthma was due to pollen allergy, 14 which means that an important number of patients were only exposed to their main asthma trigger during the pollen season, remaining asymptomatic for the rest of the year. Thus, most patients included in our study were evaluated whilst asymptomatic.…”

Section: Discussionmentioning

confidence: 99%

“…We would also like to highlight that pre-and post-normalization data has been presented and analyzed to emphasize the need for this statistical tool. Moreover, a sex-specific approach is recommended in the literature for FA and asthma in children and adolescents, 14,[21][22][23] but it is usually mentioned as a sub-analysis, not included in the primary study design. We can observe in this study how statistically significant differences appear after age and sex normalization that were not present before applying these corrections.…”

Section: Discussionmentioning

confidence: 99%

“…13 Alergológica 2015, a Spanish nationwide study, performed by selected allergists from the Spanish Allergy Society filling in electronic case reports, diagnosed FA with skin prick tests (SPT), specific IgE and oral challenges in selected patients (approximately a quarter of the total). 14 This study showed that 20% of children had FA, which was the third most important allergic condition, after rhinitis and asthma, 14 while it was the fifth allergic condition in adults, with a 10.4% prevalence. 15 There are several cross-reactivity syndromes between aeroallergens and food allergens, 16 such as protein family 10 (PR-10), 17 lipid transfer protein (LTP), 18 profilin, 19 tropomyosin, 20 etc., that can explain a direct link between FA and asthma.…”

Section: Introductionmentioning

confidence: 91%

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Food allergy as an asthma comorbidity in children and adolescents: a practical approach through a real-world study

Esteban-Gorgojo¹,

Gorgojo²,

Sastre

et al. 2021

aei

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Introduction: Several studies have shown interactions between food allergy (FA) and asthma, but the influence of FA in asthma traits has been scarcely studied. Methods: A real-world retrospective observational study was conducted among patients between 3 and 18 years old referred to our Asthma Clinic from November 2014 to November 2017. Data were obtained from daily clinical practice. Only patients properly diagnosed with asthma and FA were included. Results: 815 patients were included: 483 asthmatics and 332 non-asthmatics and 180 FA and 635 no FA. Food allergy was statistically more prevalent among asthma patients (p = 0.014). In a high pollen exposure area, Madrid, among subjects with asthma (121 FA, 362 no-FA), sensitization to lipid transfer protein (LTP) (p = 0.016, OR: 3.064, RR: 2.512) and pollen (p = 0.016, OR: 3.064, RR: 2.512) are risk factors to have a concomitant FA diagnosis, whereas sensitization to profilin is not. Peripheral blood eosinophils were higher in subjects with asthma and FA (≥450 eos/µL) than in asthmatics without FA (≤300 eos/µL) (p = 0.031). Blood eosinophilia, using a cut-off >300 eos/µL, was only present in the FA group. Therefore, this trait should be considered when phenotyping a patient as eosinophilic asthma. Sex had an impact on several variables: height, weight, BMI, blood eosinophils count, sensitization profile, and early-onset asthma. Conclusions: Asthma and FA are closely related and the presence of FA should be investigated in every asthma patient. This study shows an association between asthma with concomitant FA and sensitization to pollen and LTP, blood eosinophilia, and growth alterations. Differences between boys and girls were also described, so a sex-specific approach is recommended.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 91%

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Food allergy as an asthma comorbidity in children and adolescents: a practical approach through a real-world study

Esteban-Gorgojo¹,

Gorgojo²,

Sastre

et al. 2021

aei

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“…Los datos se compararon con los de los estudios de 1992 y 2005. La rinoconjuntivitis fue el principal motivo de consulta, que afectó a 52.5 % de pacientes adultos y 53.8 % de pacientes pediátricos, 14 ligeramente inferior a los estudios previos. La etiología fue alérgica en 79.3 % de los casos.…”

Section: Españaunclassified

“…En la población general, según los datos del European Community Health Survey, la prevalencia de asma en España es baja, con una notable variabilidad regional (Albacete, 10 %; Barcelona, 5 %; Galdácano, 14.5 %; y Oviedo, 9.4 %). 17 En Alergológica 2015, 21.2 % de los pacientes que acudían a consultas de alergia presentaba asma bronquial; 13,14 fue intermitente en 38.3 % y persistente en 57.5 %. El control, según GINA, fue bueno en 35 %, parcial en 31 % y malo en 10 %.…”

Section: Españaunclassified

Resumen ejecutivo de ARIA 2019: Vías integradas de atención para la rinitis alérgica en Argentina, España y México.

Ivancevich¹,

Cardona²,

Larenas‐Linnemann³

et al. 2019

RAM

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El impacto sanitario y económico de las enfermedades alérgicas está aumentando rápidamente y se necesitan cambios en las estrategias para su manejo. Su influencia reduce al menos en un tercio la capacidad de desempeño laboral y escolar. Los ICP (Vías Integradas de Atención) de las enfermedades de las vías respiratorias son planes de atención estructurados y multidisciplinarios, que promueven las recomendaciones de las guías en protocolos locales y su aplicación a la práctica clínica. En este documento se presenta un resumen ejecutivo para Argentina, México y España. Se desarrollan las guías ARIA de próxima generación para el tratamiento farmacológico de la rinitis alérgica (RA) utilizando las pautas basadas en GRADE para RA, probadas con evidencia de la vida real proporcionada por tecnología móvil basada en escalas visuales analógicas. Se concluye que en el tratamiento de la RA, los antihistamínicos anti-H1 son menos efectivos que los corticoides intranasales (CINS), que en la rinitis grave los CINS representan la primera línea de tratamiento, y que la combinación intranasal de CINS + anti-H1 es más eficaz que la monoterapia. Sin embargo, según el estudio MASK observacional en vida real, los pacientes tienen pobre adherencia al tratamiento y frecuentemente se automedican de acuerdo con sus necesidades.

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Preference for sublingual immunotherapy with tablets in a Spanish population with allergic rhinitis

Bøgelund¹,

Rosado

Ruiz³

et al. 2022

Clinical & Translational All

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Background This study investigated patients' preference for allergy immunotherapy (AIT) administered as either sublingual immunotherapy‐tablets versus monthly or weekly subcutaneous immunotherapy (SCIT) from a Spanish patient perspective. Methods A discrete choice experiment (DCE) consisting of two blocks with eight choice sets in each was constructed to elicit the preferences for AIT. Three attributes were included in the DCE for the mode of administration, including the frequency of administration, the risk of systemic reactions and the co‐payment. Adults and caregivers of children with moderate to severe allergic rhinitis (AR) were included if they were not currently receiving or had not previously received AIT. Results In total, 587 adults and 613 caregivers started the survey. Of those, 579 adults and 611 caregivers completed the survey and were included in the study. Both adults and caregivers had a significant preference for tablets compared with both monthly and weekly injections ( p ≤ 0.0001). Furthermore, the respondents showed a significant preference for reducing the risk of systemic reactions. Subgroup analyses showed that caregivers of polyallergic children and female caregivers were significantly less price sensitive when choosing their preferred treatment. Conclusion Our study demonstrated that both adults with AR and caregivers of children with AR prefer daily SLIT‐tablets to SCIT with either a weekly or monthly dose schedule.

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Alergólogica 2015: A National Survey on Allergic Diseases in the Spanish Pediatric Population

Cited by 28 publications

References 0 publications

Food allergy as an asthma comorbidity in children and adolescents: a practical approach through a real-world study

Food allergy as an asthma comorbidity in children and adolescents: a practical approach through a real-world study

Resumen ejecutivo de ARIA 2019: Vías integradas de atención para la rinitis alérgica en Argentina, España y México.

Preference for sublingual immunotherapy with tablets in a Spanish population with allergic rhinitis

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