Abstract:In order to develop new methodology for stereospecific and catalytic aldol reactions, synthetic organic chemists are now exploring the utility of biological catalysts. There has been significant progress in this field and several efficient, selective, and predictable biological catalysts are now available for the asymmetric aldol reaction. Critical to metabolism, the aldolases catalyze
in vivo
aldol reactions with high chemo‐, regio‐, diastereo‐, and enantios… Show more
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