Alcohol, wine, and vascular diseases: an abundance of paradoxes

Klatsky, Arthur L.

doi:10.1152/ajpheart.01387.2007

Cited by 7 publications

(4 citation statements)

References 12 publications

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“…Alcohol intake has not been found to be associated with calcified aortic atherosclerosis 28 29. Considering the conflicting effect of alcohol on vascular diseases, which depends on the amount and the kind of drinking,30 the effect of alcohol on ulcerated plaque in the present study is inconclusive. Among various risk factors, age is the strongest and universally accepted predictor of aortic atherosclerosis,2 and it is expected to be a predictor of aortic ulcer.…”

Section: Discussioncontrasting

confidence: 63%

Ulcerated plaques in the aortic arch contribute to symptomatic multiple brain infarction

Yoshimura

Toyoda

Kuwashiro

et al. 2010

Journal of Neurology, Neurosurgery & Psychiatry

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Section: Discussioncontrasting

confidence: 63%

Ulcerated plaques in the aortic arch contribute to symptomatic multiple brain infarction

Yoshimura

Toyoda

Kuwashiro

et al. 2010

Journal of Neurology, Neurosurgery & Psychiatry

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“…12 In a study using 2005 and 2006 data from the National Survey on Drug Use and Health, 13 % of men and 8 % of women aged 65 and older reported drinking two or more drinks per day. 13 Although low to moderate levels of alcohol use can have health benefits, [14][15][16][17][18] the exact benefit dose is not known and may not be risk free. [19][20][21][22] While alcohol consumption within guidelines may be permissible in some individuals with diabetes and cardiovascular disease, alcohol is not advised with certain prescription medications and can cause serious consequences.…”

Section: Introductionmentioning

confidence: 99%

Drinking Patterns of Older Adults with Chronic Medical Conditions

et al. 2013

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BACKGROUND: Understanding alcohol consumption patterns of older adults with chronic illness is important given the aging baby boomer generation, the increase in prevalence of chronic conditions and associated medication use, and the potential consequences of excessive drinking in this population. OBJECTIVES: To estimate the prevalence of alcohol consumption patterns, including at-risk drinking, in older adults with at least one of seven common chronic conditions. DESIGN/METHODS: This descriptive study used the nationally representative 2005 Medicare Current Beneficiary Survey linked with Medicare claims. The sample included community-dwelling, fee-for-service beneficiaries 65 years and older with one or more of seven chronic conditions (Alzheimer's disease and other senile dementia, chronic obstructive pulmonary disease, depression, diabetes, heart failure, hypertension, and stroke; n=7,422). Based on selfreported alcohol consumption, individuals were categorized as nondrinkers, within-guidelines drinkers, or at-risk drinkers (exceeds guidelines). RESULTS: Overall, 30.9 % (CI 28.0-34.1 %) of older adults with at least one of seven chronic conditions reported alcohol consumption in a typical month in the past year, and 6.9 % (CI 6.0-7.8 %) reported at-risk drinking. Older adults with higher chronic disease burdens were less likely to report alcohol consumption and at-risk drinking. CONCLUSIONS: Nearly one-third of older adults with selected chronic illnesses report drinking alcohol and almost 7 % drink in excess of National Institute on Alcohol Abuse and Alcoholism (NIAAA) guidelines. It is important for physicians and patients to discuss alcohol consumption as a component of chronic illness management. In cases of at-risk drinking, providers have an opportunity to provide brief intervention or to offer referrals if needed.

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“…It has been suggested that this explains about 50% of the protective effect of moderate alcohol consumption (of any type) against coronary artery disease (CAD) [122]. Increased plasma cholesterol concentrations are a well-established risk factor for CVD, and HDL-cholesterol particles return cholesterol from peripheral tissues to the liver for disposal.…”

Section: Increased Hdlmentioning

confidence: 99%

Cardiovascular Diseases

PhD¹,

Gerber²

2011

The Mediterranean Diet

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It has been hypothesized that Helicobacter pylori (Hp) infection may contribute to reduced stature, risk of hypertension or obesity. The aim was to evaluate body indices in Hp positive and negative persons. A total of 2436 subjects (4-100 years old) were tested for Hp status by 13 C-urea breath test. Data on height and weight were collected for 84%, and blood pressure for 80% of the study subjects. The prevalence of Hp infection was 41.6%. The odds ratio for a 10-year increase in age was 1.21 (95% CI 1.17-1.25, p-value <0.001). Statistically significant negative association of Hp positivity with body height was most pronounced in the younger age groups, while a positive association of Hp positivity with body mass index was only seen in those aged 15+ years. There was a negative effect of Hp positivity on systolic and diastolic blood pressure in subjects below 25 and a relatively strong positive effect on blood pressure in subjects over 65 years. Residual confounding by social characteristics as a possible explanation for the associations of Hp positivity with height and blood pressure cannot be excluded. Unmeasured factors related to social and family environment may cause the apparent association between Hp positivity and children's growth and blood pressure.

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Alcohol, wine, and vascular diseases: an abundance of paradoxes

Cited by 7 publications

References 12 publications

Ulcerated plaques in the aortic arch contribute to symptomatic multiple brain infarction

Ulcerated plaques in the aortic arch contribute to symptomatic multiple brain infarction

Drinking Patterns of Older Adults with Chronic Medical Conditions

Cardiovascular Diseases

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