Alcohol use in late adolescence and early adulthood: The role of generalized anxiety disorder and drinking to cope motives

Dyer, Maddy; Heron, Jon; Hickman, Matthew; Munafò, Marcus R.

doi:10.1016/j.drugalcdep.2019.04.044

“…Some observational studies support the moderating role of DTC on the relationship between anxiety and alcohol use (Grant et al, 2009). However, we found no clear evidence that DTC moderates associations between generalised anxiety disorder (GAD) and alcohol use in a large cohort study of adolescent drinkers (Dyer et al, 2019). DTC may instead moderate the relationship between state anxiety and alcohol outcomes.…”

Section: Introductioncontrasting

confidence: 72%

State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies

Dyer¹,

Board²,

Hogarth³

et al. 2020

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We conducted two experiments using the 7.5% carbon dioxide challenge (Studies 1 and 2) and an observational study (Study 3) to investigate the relationships between state anxiety and alcohol-related outcomes (primarily alcohol choice) (ns = 42, 60, 218, respectively). We also explored whether drinking to cope (DTC) motives moderated these relationships. In Study 1, experimentally-induced state anxiety increased alcohol choice (dz = .65, p <.001). This finding was replicated in Study 2, but the effect was weaker (ηp2 = .056, p = .076). Furthermore, DTC moderated the effect (ηp 2 = .106, p = .013). However, in Study 3 there was no clear evidence of an association between naturally-occurring state anxiety and alcohol choice (b = 0.05, p = .654), or a moderating role of DTC (b = 6.66, p = .311). Experimentally-induced, but not naturally-occurring, state anxiety increases alcohol choice, although state anxiety was lower in the non-manipulated sample.

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“…In addition, the age of onset of anxiety and mood disorders differs, with anxiety disorders starting at earlier ages and mood disorders being more prevalent in late adolescence/young adulthood, with evidence that the peak acceleration in depressed mood is age 13 for females and age 16 for males (13,107,108). Further, internalising problems often present as comorbid with other disorders in children and adolescents (109,110), and often precede other psychiatric disorders (12,111,112). The quality of parent-child relationships in early childhood represents a unique time window for child emotional and social development (44), providing a potentially salient period for prevention and intervention.…”

Section: Discussionmentioning

confidence: 99%

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents. 

Costantini

¹

,

Paul

²

,

Caldwell

³

et al. 2020

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0

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Background: Internalising problems, such as depression and anxiety, are common and represent an important economical and societal burden. The effectiveness of parenting interventions in reducing risk of internalising problems in children and adolescents has not yet been summarised. The aims of this review are to assess the effectiveness of parenting interventions in the primary, secondary and tertiary prevention of internalising problems in children and adolescents and to determine which intervention components and which intervention aspects are most effective for reducing risk of internalising problems in children and adolescents. Methods: Electronic searches in OVID SP versions of Medline, EMBASE and PsycINFO; Cochrane Central Register of Controlled Trials; EBSCO version of ERIC and clinicaltrials.gov have been performed to identify randomised controlled trials or quasi-randomised controlled trials of parenting interventions. At least two independent researchers will assess studies for inclusion and extract data from each paper. The risk of bias assessment will be conducted independently by two reviewers using the Cochrane Collaboration’s Risk of Bias Assessment Tool. Statistical heterogeneity is anticipated given potential variation in participant characteristics, intervention type and mode of delivery, and outcome measures. Random effects models, assuming a common between-study variability, will be used to account for statistical heterogeneity. Results will be analysed using a network meta-analysis (NMA). If appropriate, we will also conduct a component-level NMA, where the ‘active ingredients’ of interventions are modelled using a network meta-regression approach.Discussion: Preventing and reducing internalising problems could have major beneficial effects at the economic and societal level. Informing policy makers on the effectiveness of parenting interventions and on which intervention’s component is driving the effect is important for the development of treatment strategies. Systematic review registration: International Prospective Register for Systematic Reviews (PROSPERO) number CRD42020172251

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“…In addition, the age of onset of anxiety and mood disorders differs, with anxiety disorders starting at earlier ages and mood disorders being more prevalent in late adolescence/young adulthood, with evidence that the peak acceleration in depressed mood is age 13 for females and age 16 for males (13,109,110). Further, internalising problems often present as comorbid with other disorders in children and adolescents (111,112), and often precede other psychiatric disorders (12,113,114). The quality of parent-child relationships in early childhood represents a unique time window for child emotional and social development (44), providing a potentially salient period for prevention and intervention.…”

Section: Discussionmentioning

confidence: 99%

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.

Costantini

¹

,

Paul

²

,

Caldwell

³

et al. 2020

Preprint

0

View full text Add to dashboard Cite

Background: Internalising problems, such as depression and anxiety, are common and represent an important economical and societal burden. The effectiveness of parenting interventions in reducing risk of internalising problems in children and adolescents has not yet been summarised. The aims of this review are to assess the effectiveness of parenting interventions in the primary, secondary and tertiary prevention of internalising problems in children and adolescents and to determine which intervention components and which intervention aspects are most effective for reducing risk of internalising problems in children and adolescents. Methods: Electronic searches in OVID SP versions of Medline, EMBASE and PsycINFO; Cochrane Central Register of Controlled Trials; EBSCO version of ERIC and clinicaltrials.gov have been performed to identify randomised controlled trials or quasi-randomised controlled trials of parenting interventions. At least two independent researchers will assess studies for inclusion and extract data from each paper. The risk of bias assessment will be conducted independently by two reviewers using the Cochrane Collaboration’s Risk of Bias Assessment Tool. Statistical heterogeneity is anticipated given potential variation in participant characteristics, intervention type and mode of delivery, and outcome measures. Random effects models, assuming a common between-study variability, will be used to account for statistical heterogeneity. Results will be analysed using a network meta-analysis (NMA). If appropriate, we will also conduct a component-level NMA, where the ‘active ingredients’ of interventions are modelled using a network meta-regression approach.Discussion: Preventing and reducing internalising problems could have major beneficial effects at the economic and societal level. Informing policy makers on the effectiveness of parenting interventions and on which intervention’s component is driving the effect is important for the development of treatment strategies. Systematic review registration: International Prospective Register for Systematic Reviews (PROSPERO) number CRD42020172251

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Alcohol use in late adolescence and early adulthood: The role of generalized anxiety disorder and drinking to cope motives

Abstract: HighlightsGeneralized anxiety is positively associated with alcohol use in adolescence.In early adulthood, associations remain for harmful drinking only.Associations are not moderated by drinking to cope motives.

Cited by 21 publications

References 40 publications

State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies

State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.

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Alcohol use in late adolescence and early adulthood: The role of generalized anxiety disorder and drinking to cope motives

Abstract: HighlightsGeneralized anxiety is positively associated with alcohol use in adolescence.In early adulthood, associations remain for harmful drinking only.Associations are not moderated by drinking to cope motives.

Cited by 21 publications

References 40 publications

State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies

State Anxiety and Alcohol Choice: Evidence from Experimental and Online Observational Studies

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.&nbsp;

Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.

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Product

Resources

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Protocol for a systematic review and network meta-analysis of randomised controlled trials examining the effectiveness of early parenting interventions in preventing internalising problems in children and adolescents.