Alcohol use associated alterations in the circulating metabolite profile in the general population and in individuals with major depressive disorder
Olli Kärkkäinen,
Tommi Tolmunen,
Petri Kivimäki
et al.
Abstract:Our aim was to evaluate whether alcohol use is associated with changes in the circulating metabolite profile similar to those present in persons with depression. If so, these findings could partially explain the link between alcohol use and depression. We applied a targeted liquid chromatography mass spectrometry method to evaluate correlates between concentrations of 86 circulating metabolites and self-reported alcohol use in a cohort of the non-depressed general population (GP) (n = 247) and a cohort of indi… Show more
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