“…Global association studies typically suggest a positive association between aggregate substance use and sexual risk behaviors in the general population (Leigh and Stall, 1993) as well as among GBMSM, with positive associations found between condomless anal sex (CAS) and frequent alcohol use (Morin et al, 2005; Tawk et al, 2004), heavy alcohol use (Colfax et al, 2004; Koblin et al, 2003; Woody et al, 1999), and any use of marijuana (Koblin et al, 2003) or club drugs, including cocaine, MDMA/ecstasy, methamphetamine, GHB, and ketamine (Colfax et al, 2005; Drumright et al, 2006b; Klitzman et al, 2002; Koblin et al, 2003; Purcell et al, 2001, 2005; Rusch et al, 2004; Woody et al, 1999). In addition to increased risk of CAS, recent studies continue to support associations between global alcohol and drug use and an increased number of sexual partners (Greenwood et al, 2001; Klitzman et al, 2002; Pollock et al, 2012). For example, Klitzman and colleagues found that, compared to low frequency MDMA users, higher frequency MDMA users had more sex partners and more âone night standsâ (Klitzman et al, 2002).…”