Abstract:Some medications when taken with alcohol cause accumulation of acetaldehyde by inhibiting aldehyde dehydrogenase (ALDH) enzyme. Acetaldehyde causes toxic effects in the body which are characterized by nausea, vomiting, facial flushing, hypotension and tachycardia, symptoms known as disulfiram-like reactions/antabuse effects or acetaldehyde syndrome. Alcohol interacts with many medications, thereby altering the metabolism of medications and/or alcohol. Alcohol dependence is an increasing and pervasive issue in … Show more
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