Alcohol-Endocrine Interrelationships

Stokes, Peter E.

doi:10.1007/978-1-4615-6525-3_13

Cited by 17 publications

(5 citation statements)

References 81 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Within the total group, slightly higher mean values than that of unipolar de-pression were found in patients with acute brain syndrome and in alcohol abusers with various clinical diagnoses. This observation is consistent with the abnormalities of HPA reported during alcohol withdrawal (see review by Stokes, 1974) and in patients with organic brain syndrome (Krieger & Krieger, 1966;Suwa et al 1974). This suggests that evening plasma cortisol levels cannot be used to study patients with depression, for example, unless abuse of alcohol or the presence of organic brain syndrome are excluded.…”

Section: Discussionsupporting

confidence: 83%

Plasma cortisol levels in depression and other psychiatric disorders: a study of newly admitted psychiatric patients

1979

View full text Add to dashboard Cite

SynopsisMorning and evening plasma cortisol levels were checked in 123 consecutively newly admitted psychiatric patients with a variety of diagnoses. Questions asked were whether there were differences among groups with more severe illness, type of depression, alcohol abuse, or particular symptoms. Morning cortisol elevation was found in 33% of patients and was not associated with any particular diagnostic category. Evening cortisol elevation occurred in 85% of the subjects. It was significantly higher in those with unipolar depression and organic brain syndrome, also in those patients who abused alcohol regardless of diagnosis. Evening cortisol elevation was twice as common in patients with diagnoses of more severe psychiatric illness than in those with minor disorders. Further study is suggested to see if these patterns of cortisol elevation are sustained beyond the stress-of-admission period.

show abstract

Section: Discussionsupporting

confidence: 83%

Plasma cortisol levels in depression and other psychiatric disorders: a study of newly admitted psychiatric patients

1979

View full text Add to dashboard Cite

show abstract

“…A third example of physiological adaptation to chronic alcohol intake is found in the functioning of the hypothalamic-pituitary-adrenal axis. Ingested ethanol stimulates the axis, resulting in elevated levels of corticosteroids (particularly cortisol) and biogenic amines (especially epinephrine) in the blood and urine (Mendelson, Ogata, & Mello, 1971;Noble, 1973;Ogata, Mendelson, Mello, & Majchrowicz, 1971;Stokes, 1971). There is some evidence from research with animals and humans that with prolonged alcohol intake, a degree of adaptation occurs in this system (Kalant, 1962;Noble, 1973), although the extent of adaptation in humans is still unclear (Stokes, 1971).…”

Section: Physiological Adaptationmentioning

confidence: 99%

“…Ingested ethanol stimulates the axis, resulting in elevated levels of corticosteroids (particularly cortisol) and biogenic amines (especially epinephrine) in the blood and urine (Mendelson, Ogata, & Mello, 1971;Noble, 1973;Ogata, Mendelson, Mello, & Majchrowicz, 1971;Stokes, 1971). There is some evidence from research with animals and humans that with prolonged alcohol intake, a degree of adaptation occurs in this system (Kalant, 1962;Noble, 1973), although the extent of adaptation in humans is still unclear (Stokes, 1971). tracked the serum cortisol levels of alcoholics and nonalcoholics during 4 days of drinking and 3 subsequent days of withdrawal.…”

Section: Physiological Adaptationmentioning

confidence: 99%

Alcoholism scales and objective assessment methods: A review.

Miller¹

1976

Psychological Bulletin

146

View full text Add to dashboard Cite

Research attempting to differentiate alcoholics from other groups is reviewed, with special attention being devoted to the validity of available diagnostic instruments. The review is divided into sections on special alcoholism scales, personality measures, physiological variables, behavioral assessment techniques, and longitudinal research. No single method has been found to be completely satisfactory for diagnosis, and the use of multimodal assessment is encouraged. Differential assessment is presented as an alternative to the binary nosology of alcoholic versus nonalcoholic. Implications for future research and diagnostic practices are discussed.

show abstract

“…In addition, there are complex effects of sedatives on many hormonal systems (see e.g. GORSKI, 1974;STOKES, 1971).…”

Section: Interactions With Hormones Antagonists and Metabolic Produmentioning

confidence: 99%

The Pharmacology of Sedative/Hypnotics, Alcohol, and Anesthetics: Sites and Mechanisms of Action

Smith¹

1977

Drug Addiction I

View full text Add to dashboard Cite

Alcohol-Endocrine Interrelationships

Cited by 17 publications

References 81 publications

Plasma cortisol levels in depression and other psychiatric disorders: a study of newly admitted psychiatric patients

Plasma cortisol levels in depression and other psychiatric disorders: a study of newly admitted psychiatric patients

Alcoholism scales and objective assessment methods: A review.

The Pharmacology of Sedative/Hypnotics, Alcohol, and Anesthetics: Sites and Mechanisms of Action

Contact Info

Product

Resources

About