Alcohol consumption predicts incidence of depressive episodes across 10 years among older adults in 19 countries

Keyes, Katherine M.; Allel, Kasim; Staudinger, Ursula M.; Ornstein, Katherine; Calvo, Esteban

doi:10.1016/bs.irn.2019.09.001

Cited by 43 publications

(33 citation statements)

References 104 publications

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“…People with depressive symptoms can be at increased risk of unhealthy lifestyle behaviors including excessive alcohol drinking, smoking, substance abuse, inadequate physical activity and obesity; thus, depression may affect mortality through its negative effects on health behaviors 36 , 37 . Exercise has also been suggested to improve depressive symptoms 38 , while smoking 39 and alcohol consumption 40 have shown a potential association with subsequent depression. Depressive symptoms might also negatively affect use of healthcare services and compliance with treatment, and therefore adversely affect health outcomes.…”

Section: Discussionmentioning

confidence: 99%

Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study

Cho

Chang

Sung

et al. 2020

Sci Rep

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The impact of depression on the risk of liver-related mortality in individuals with hepatitis B virus (HBV) infection remains unclear. We examined the association between depression, HBV infection, and liver-related mortality. A total of 342,998 Korean adults who underwent health examinations were followed for up to 7.8 years. Depressive symptoms were defined as a Center for Epidemiologic Studies-Depression score ≥ 16. Cox proportional hazard models were used to estimate adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs). During 1,836,508 person-years of follow-up, 74 liver-related deaths and 54 liver cancer deaths were identified (liver-related mortality rate of 4.0 per 105 person-years and liver cancer mortality rate of 2.9 per 105 person-years). Subjects with depressive symptoms had an increased risk of liver-related mortality with a corresponding multivariable aHR of 2.00 (95% CI 1.10–3.63) compared to those without depressive symptoms. This association was more evident in HBsAg-positive participants with a corresponding multivariable aHR of 4.22 (95% CI 1.81–9.88) than HBsAg-negative participants (P for interaction by HBsAg positivity = 0.036). A similar pattern was observed in relation to liver cancer mortality. In this large cohort, depressive symptoms were associated with an increased risk of liver-related mortality, with a stronger association in HBsAg-positive individuals.

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Section: Discussionmentioning

confidence: 99%

Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study

Cho

Chang

Sung

et al. 2020

Sci Rep

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“…These age-related changes result in more intoxications and potential harm among older adults, especially if they interact and interfere with their treatments and medications [20][21][22]. Heavy drinking is thus particularly detrimental to older adults' health, including cognition [23][24][25], depression [26], falls [23] and survival [27]. Although many studies show a beneficial association between drinking and health in old age, these findings are probably due to selection effects as older drinkers tend to remain drinking if they are healthy, while recent abstainers (as opposed to life-time abstainers) may be 'sick quitters' [28].…”

Section: Introductionmentioning

confidence: 99%

Cross‐country differences in age trends in alcohol consumption among older adults: a cross‐sectional study of individuals aged 50 years and older in 22 countries

et al. 2020

Self Cite

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Background and Aims Age‐related changes in physiological, metabolic and medication profiles make alcohol consumption likely to be more harmful among older than younger adults. This study aimed to estimate cross‐national variation in the quantity and patterns of drinking throughout older age, and to investigate country‐level variables explaining cross‐national variation in consumption for individuals aged 50 years and older. Design Cross‐sectional observational study using previously harmonized survey data. Setting Twenty‐two countries surveyed in 2010 or the closest available year. Participants A total of 106 180 adults aged 50 years and over. Measurements Cross‐national variation in age trends were estimated for two outcomes: weekly number of standard drink units (SDUs) and patterns of alcohol consumption (never, ever, occasional, moderate and heavy drinking). Human Development Index and average prices of vodka were used as country‐level variables moderating age‐related declines in drinking. Findings Alcohol consumption was negatively associated with age (risk ratio = 0.98; 95% confidence interval = 0.97, 0.99; P‐value < 0.001), but there was substantial cross‐country variation in the age‐related differences in alcohol consumption [likelihood ratio (LR) test P‐value < 0.001], even after adjusting for the composition of populations. Countries’ development level and alcohol prices explained 31% of cross‐country variability in SDUs (LR test P‐value < 0.001) but did not explain cross‐country variability in the prevalence of heavy drinkers. Conclusions Use and harmful use of alcohol among older adults appears to vary widely across age and countries. This variation can be partly explained both by the country‐specific composition of populations and country‐level contextual factors such as development level and alcohol prices.

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“…Unexpectedly, we did not identify an association between excessive alcohol consumption and mental distress, as the significant association observed among females disappeared after adjustment for BMI, perceived financial situation, and age. Evidence from other studies, however, confirmed an association between high alcohol consumption and the prevalence of mental distress among both genders [21,51,52]. A cross-sectional study among Korean adults concluded that the risk of mental distress was associated with the severity of alcohol-related problems and that the association appeared to be more evident among females than males [53].…”

Section: Discussionmentioning

confidence: 95%

The Association between Dietary Habits, Substance Use, and Mental Distress among Adults in Southern Norway: A Cross-Sectional Study among 28,047 Adults from the General Population

Stea

Alvsvåg

Kleppang

2021

IJERPH

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The aim of the present study was to examine associations between dietary habits, substance use, and mental distress among adults. This cross-sectional study was conducted in 2019 using an online questionnaire and included 28,047 adults (≥18 years) from Southern Norway. Multivariable logistic regression models stratified by gender were used to examine the associations between different lifestyle behaviors and mental distress. The results showed increased odds of mental distress among males and females with low consumption of vegetables (OR:1.26; 95% CI:1.08–1.47 and 1.14; 1.02–1.28) and fish (1.28; 1.12–1.46 and 1.36; 1.22–1.52), and among females, but not males, with high consumption of sugar-sweetened beverages (1.25; 1.06–1.48) compared to those with a healthier consumption of these foods and beverages. The results also showed increased odds of mental distress among male and female smokers (1.38; 1.19–1.60 and 1.44; 1.26–1.64), and among females, but not males, reporting current use of smokeless tobacco (1.20; 1.03–1.40), compared to male and female non-smokers and female non-users of smokeless tobacco. Overall, unhealthy dietary habits, smoking and the use of smokeless tobacco was associated with increased odds of mental distress, but the relationship varied according to gender. Future studies are needed to confirm any possible causal relationships.

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Alcohol consumption predicts incidence of depressive episodes across 10 years among older adults in 19 countries

Cited by 43 publications

References 104 publications

Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study

Depressive symptoms and risk of liver-related mortality in individuals with hepatitis B virus infection: a cohort study

Cross‐country differences in age trends in alcohol consumption among older adults: a cross‐sectional study of individuals aged 50 years and older in 22 countries

The Association between Dietary Habits, Substance Use, and Mental Distress among Adults in Southern Norway: A Cross-Sectional Study among 28,047 Adults from the General Population

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