Alcohol and delirium tremens: effects of average number of drinks per day and beverage type

Sørensen, Holger J.; Holst, Charlotte; Knop, Joachim; Mortensen, Erik Lykke; Tolstrup, Janne S; Becker, Ulrik

doi:10.1111/acps.13006

Cited by 7 publications

(9 citation statements)

References 26 publications

(28 reference statements)

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“…In other bivariate analyses both parental drinking and how much alcohol the person could take (SRE) were also related to DT, indicating that patients with more severe AUD were most at risk of DT. 7 In the present study patients with DT experience reported 12–16 units of alcohol being required to produce an effect, which is lower than the 20 units reported among DT in a Danish study, 32 possibly related to higher population-level of alcohol consumption in Denmark than in Norway.…”

Section: Discussioncontrasting

confidence: 77%

“…This is in line with previous studies showing that males are more at risk for DT, maybe due to more intense drinking. 32 Other studies correcting for level of drinking fail to find a sex effect. 7 Also in the present study, low educational level and male sex may be less important than other clinical features as these background variables were related to duration of problematic drinking and self-reported effects of alcohol.…”

Section: Discussionmentioning

confidence: 98%

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History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors

Bramness¹,

Pandey²,

Moe³

et al. 2022

SAR

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Introduction Delirium tremens (DT) occurs after stopping prolonged, high alcohol intake and may be life-threatening if untreated. We need to know about clinical correlates of DT in order to provide the best clinical care. Methods At admission to inpatient treatment a cohort of 114 alcohol use disorder (AUD) patients were interviewed and examined concerning psychiatric diagnosis and symptoms, trauma experiences and alcohol related measures and if they had experienced DT. Results Twenty-four percent of the patients reported a life-time experience of DT. These patients were predominantly males and had lower educational level. More of the patients in the DT than the non-DT group reported at least one suicide attempt, were diagnosed with PTSD, and dropped out of treatment. Also, having parents with alcohol problems was more common among these patients, and they reported a longer duration of problematic drinking and a higher number of drinks needed to feel an effect of drinking. In the multivariable adjusted analysis only a diagnosis of PTSD (OR=5.71; 95% confidence interval (CI): 1.34–24.31) and duration of problematic drinking with a 6% increase in risk for every year (OR=1.06; 95% CI: 1.01–1.11) remained significant risk factors for having DT experience. Discussion and conclusion Having experienced DT was more prevalent in the current investigation than in earlier studies. Patients that had experienced DT seemed to have more serious AUD, especially signified by a longer duration of drinking. These patients seemed to have many clinical disadvantages including more drop-out and higher suicide rate. PTSD could be a risk factor for DT but may also follow the DT experience.

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Section: Discussioncontrasting

confidence: 77%

Section: Discussionmentioning

confidence: 98%

History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors

Bramness¹,

Pandey²,

Moe³

et al. 2022

SAR

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“…Long-term drinking with addiction causes severe mental health problems such as "Korsakoff Syndrome" (Ritz et al, 2021) and "Delirium Tremens" (Calvo et al, 2018). Especially "delirium tremens", also known as alcohol withdrawal syndrome, occurs after the individual suddenly reduces or quits alcohol, so alcohol addiction becomes more lethal (Sørensen et al, 2019). The author explains below, using a funny memory, that his father diagnosed this in one of his patients as follows:…”

Section: Biological Causal Factorsmentioning

confidence: 99%

Using Literary Works to Teach Psychopathology: A Qualitative Document Analysis Regarding Alcohol Use Disorder

Kaya¹

2022

IJPES

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Bringing real-life cases to the educational environment and presenting them to students is one of the main goals of psychology. However, this is unfortunately not as easy as it is said, both ethically and practically. Since the educational materials to be offered to students on this subject are insufficient, academics and lecturers recommend that their students read case studies in psychopathology lessons or watch videos depicting certain disorders. While the use of films in both national and international literature in psychology and psychological counselling theories and practices is increasing, it is thought-provoking that there is no similar interest/attempt in reading literary works. Despite the (not)reading rates, the using literary works in students' education is overshadowed by films constitutes the main motivation of this studyusing literary works in students' education is overshadowed by films, which constitutes this study's main motivation. In this sense, the main purpose of the research is to provide an example of how literary works can be used in psychopathology teaching.

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“…Постинтоксикационный делирий (ПД) является тяжелым осложнением систематического употребления психоактивных веществ и одним из основных факторов повышенного риска летального исхода, что обусловливает актуальность работы [1][2][3][4][5][6].…”

Section: Introductionunclassified

Delirium in Acute Poisoning with 1,4-Butanediol and Its Correction

Sinenchenko

Lodyagin

Sinenchenko

et al. 2021

Obŝaâ reanimatologiâ

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Delirium complicating regular use of psychoactive substances remains one of the major issues of critical care, toxicology, and psychiatry. However, the pathogenetic mechanisms of delirium development in patients with 1,4-butanediol poisoning have been poorly studied until now.The aim of the study was to reveal specific patterns of delirium in patients with 1,4-butanediol poisoning as well as to study the changes in systemic hemodynamic parameters, respiratory function, and body fluid compartments during the treatment.Material and methods. The study was prospective and treatment-randomized. Forty-eight male patients aged 20 to 45 years with delirium and acute 1,4-butanediol poisoning were enrolled. Of them, 24 patients were administered with succinate-containing drug 40 ml daily, 24 patients received standard treatment without antihypoxic agents. We studied the evolution of delirium, changes in anaerobic metabolism parameters, systemic hemodynamics, respiratory function, and the volume of fluid compartments. Impedance measurement method adjusted for interference was used in the study.Results. At the «peak» of delirium (days 1–3), the hyperdynamic circulation, increased systemic arterial tone, stroke output, respiratory function parameters, and metabolic lactate acidosis were recorded. A decrease in total fluid volume and extracellular fluid volume was clearly observed during day 1 of intoxication delirium along with increased permeability of cell membranes. On day 3 of delirium, a decrease in intracellular fluid volume and increase in extracellular fluid volume were noted. After the cytoflavin administration, shorter delirium duration (7.5 [6; 8] days), more rapid correction of lactate acidosis, stabilization of respiratory parameters and stabilization of cell membrane permeability by day 5 were found. In the control group, delirium persisted for up to 14 [11; 15] days (z=-5.9; P=0.00011) with more frequent development of complications such as nosocomial pneumonia (χ2=8.4, P<0.001).Conclusion. The severity of delirium in acute poisoning with 1,4-butanediol was associated with metabolic lactate acidosis, changes in systemic hemodynamics and pulmonary function. A positive effect of adjunctive antihypoxic therapy with succinate-containing agent on cardio-respiratory parameters, cell membrane permeability, water balance due to elimination of tissue hypoxia and prompt switching to tissue aerobic metabolism has been found.

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Alcohol and delirium tremens: effects of average number of drinks per day and beverage type

Cited by 7 publications

References 26 publications

History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors

History of Delirium Tremens in AUD Patients in Treatment: Relationship to AUD Severity and Other Factors

Using Literary Works to Teach Psychopathology: A Qualitative Document Analysis Regarding Alcohol Use Disorder

Delirium in Acute Poisoning with 1,4-Butanediol and Its Correction

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