Alcohol and Aggression: Theories and Mechanisms

Giancola, Peter R.

doi:10.1002/9781118411094.ch3

Cited by 11 publications

(21 citation statements)

References 85 publications

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“…Other research shows that those who experience childhood abuse are also more likely to experience bullying at school 72 , begging the question of whether family history of alcoholism may ultimately increase risk for bullying victimization and/or perpetration via risk for childhood abuse. To the extent that alcohol use decreases inhibitions or causes personality changes such as increased anger or aggression 73,74 , those who drink in response to bullying may also be more likely to become perpetrators in the future. Clearly, future research would benefit from incorporating validated measures of personality and family history of alcoholism, assessing history of child abuse, and assessing bullying perpetration in addition to victimization.…”

Section: Discussionmentioning

confidence: 99%

Bullying Victimization Among College Students: Negative Consequences for Alcohol Use

Rospenda

Richman

Wolff

et al. 2013

Journal of Addictive Diseases

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This study reports on the prevalence of bullying victimization at school and work among college freshmen, and the relationships between victimization and changes in alcohol consumption and alcohol problems. Web survey data at two points in time from a sample of 2118 freshmen from eight colleges and universities in the Midwestern United States indicated that 43% of students experienced bullying at school, and 33% of students experienced bullying at work. Bullying, particularly at school, consistently predicted alcohol consumption and problematic drinking, controlling for baseline drinking and other school and work stressors.

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Section: Discussionmentioning

confidence: 99%

Bullying Victimization Among College Students: Negative Consequences for Alcohol Use

Rospenda

Richman

Wolff

et al. 2013

Journal of Addictive Diseases

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“…This link is large in magnitude and costly to the individual, family, and society . In addition to the pervasive escalation of many types of impulsive and reactive violent acts, possibly due to the myopic perception of threatening stimuli, some epidemiological data point to geographic hot spots and epidemics of the alcohol‐violence link . Rather than proposing a neurogenetic deterministic account of the genesis of alcohol‐heightened aggressive behavior, this evidence points to several risk factors that may interact with the social context …”

Section: Epidemiological Backgroundmentioning

confidence: 99%

“…The analysis of social cues and the interpretation and integration of these cues promises to reveal how alcohol alters provocative signals, and the response to these signals. Giancola proposes that distorted perceptions of social signals—a type of myopia—emerge as a key determinant of alcohol‐escalated aggressive behavior.…”

Section: Victims Of Aggression: Escalated Alcohol Consumption As a Rementioning

confidence: 99%

Alcohol and violence: neuropeptidergic modulation of monoamine systems

Miczek

DeBold

Hwa

et al. 2015

Annals of the New York Academy of Sciences

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Neurobiological processes underlying the epidemiologically-established link between alcohol and several types of social, aggressive, and violent behavior remain poorly understood. Acute low doses of alcohol, as well as withdrawal from long-term alcohol use, may lead to escalated aggressive behavior in a subset of individuals. An urgent task will be to disentangle the host of interacting genetic and environmental risk factors in individuals that are predisposed to engage in escalated aggressive behavior. The modulation of 5-hydroxytryptamine impulse flow by gamma-aminobutyric acid (GABA) and glutamate, acting via distinct ionotropic and metabotropic receptor subtypes in the dorsal raphe nucleus during alcohol consumption, is of critical significance in the suppression and escalation of aggressive behavior. In anticipation and reaction to aggressive behavior, neuropeptides such as corticotropin-releasing factor, neuropeptide Y, opioid peptides, and vasopressin interact with monoamines, GABA, and glutamate to attenuate and amplify aggressive behavior in alcohol-consuming individuals. These neuromodulators represent novel molecular targets for intervention that await clinical validation. Intermittent episodes of brief social defeat during aggressive confrontations are sufficient to cause long-lasting neuroadaptations that can lead to the escalation of alcohol consumption.

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“…A second hypothesis focuses on the considerable evidence for the anxiolytic effects of alcohol that may reduce the fear of the stranger (i.e., xenophobia) and thereby disinhibit aggressive behavior [11]. Third, the pro-aggressive effects of alcohol may stem from misperceived threatening stimuli [35]. How can animal models best examine the face validity of these alternative hypotheses for better understanding the aggression-escalating effects of alcohol?…”

Section: Animal Models Of Maladaptive Pathological Aggressionmentioning

confidence: 99%

Escalated aggression in animal models: shedding new light on mesocorticolimbic circuits

Miczek

Takahashi

Gobrogge

et al. 2015

Current Opinion in Behavioral Sciences

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Recent developments promise to significantly advance the understudied behavioral and neurobiology of aggression: (1) Animal models that capture essential features of human violence and callousness have been developed. These models range from mice that have been selectively bred for short attack latencies, monogamous prairie voles, and glucocorticoid-compromised rats to rodents and non-human primates that escalate their aggression after consuming or when withdrawing from alcohol. (2) Optogenetic stimulation and viral vector-based approaches have begun to identify overlapping and distinctive neural microcircuits and intracellular molecules for adaptive vs. excessive, maladaptive aggressive behavior in several rodent models. Projections from hypothalamic and mesencephalic neurons to the medial prefrontal cortex contain microcircuits that appear pivotal for the escalation of aggression.

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Alcohol and Aggression: Theories and Mechanisms

Cited by 11 publications

References 85 publications

Bullying Victimization Among College Students: Negative Consequences for Alcohol Use

Bullying Victimization Among College Students: Negative Consequences for Alcohol Use

Alcohol and violence: neuropeptidergic modulation of monoamine systems

Escalated aggression in animal models: shedding new light on mesocorticolimbic circuits

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