Alcohol anamnesis and a death place factor: Role in mortality rates due to leading cardiovascular diseases

Mordovsky, E A; Soloviev, A. G.; Al, Sannikov

doi:10.17116/terarkh201587926-33

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…Алкогольные напитки относятся к пищевым продуктам. Однако результаты исследований свидетельствуют о прямой зависимости между уровнем потребления алкоголя и степенью дисбаланса в характере питания, выражающемся в высоком потреблении животных жиров, соли, НЖК и низком -клетчатки и моненасыщенных жирных кислот (МНЖК) [7], а злоупотребление алкоголем можно рассматривать как усугубление нутриционной составляющей риска развития коморбидной соматической патологии [8] и в целом нарушения индивидуальной социальной безопасности трудоспособного населения в Арктическом регионе.…”

Section: Introductionunclassified

Development of alcoholic dyslipidemia syndrome — social security violation factor in the Arctic region.

Solovieva,

Solovyova,

Udovenkova

et al. 2024

TKSC RAS NSH

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Alcoholism aggravates the nutritional component of developing comorbid somatic pathology risk in the Arctic region. Against the background of alcohol dependence syndrome (ADS) development peculiar changes in lipid metabolism are revealed: a low low-density lipoproteins (LDL) and triglycerides (TG) content, but a high high-density lipoproteins (HDL) content. The revealed changes stimulate the search for new diagnostic approaches, with the help of which it is possible to identify hidden alcohol-associated changes in lipid metabolism and influence the mechanisms of cardiovascular system (CVS) pathology development at different stages. The aim was to identify lipid metabolism disorders in practically healthy individuals and in individuals with alcohol dependence to substantiate the specific clinical and biological syndrome isolation — alcoholic dyslipidemia and to develop an algorithm for detecting hidden alcohol-associated disorders. 208 men were examined: 96 people — with II stage SCA; 112 — practically healthy individuals. The content of total cholesterol, TG, HDL was determined by enzymatic colorimetric method, LDL — by turbidimetric method, concentrations of apolipoproteins (apo-A and apo-B) — by immuno-turbidimetric method, fatty acids — by gas-liquid chromatography. A low content of SFA (pentadecanoic, margarine, arachine, geneicosene), multidirectional changes in MSFA with a low content of myristooleic and eicosene lipid acids, but high palmitooleic and heptadecanoic; PUFA ω-6 linoleic, arachidonic. At the same time, an increase in the content of linoleic lipid acids trans-form was noted, the content of ω-3 PUFA was also lower than that of PP due to α-linolenic (C18:3ω3), docosohexaenoic (DHA), but the content of eicosopentaenoic (EPA) was higher. In narcological patients, weak correlations between LDL, TG and NLC were found, which indicates a lipid acids into LDL and TG integration violation. The absence of interrelations of ω-3 linoleic acid with EPA and DHA forming from it in patients with ADS may indicate anenzymatic processes violation.

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Section: Introductionunclassified

Development of alcoholic dyslipidemia syndrome — social security violation factor in the Arctic region.

Solovieva,

Solovyova,

Udovenkova

et al. 2024

TKSC RAS NSH

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Regional deprivation and risk of developing cardiovascular diseases (Framingham Risk Score): data from ESSE-RF

Zelenina¹,

Shalnova²,

Муромцева³

et al. 2023

Profil. med.

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Alcohol anamnesis and a death place factor: Role in mortality rates due to leading cardiovascular diseases

Abstract: The results of the investigation suggest that there is inequality in the excess risk of death from leading CDs among the representatives of different social population groups in Arkhangelsk, as well as nonequivalence in their interaction with the public health system.

Cited by 2 publications

References 16 publications

Development of alcoholic dyslipidemia syndrome — social security violation factor in the Arctic region.

Development of alcoholic dyslipidemia syndrome — social security violation factor in the Arctic region.

Regional deprivation and risk of developing cardiovascular diseases (Framingham Risk Score): data from ESSE-RF

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