“…In the last 3 decades, several studies have been performed in eastern and western countries on groups of subjects with alcohol addiction, reporting a significantly higher mortality in comparison with matched controls or the general population (Barr et al, 1984;Berglund, 1984;Dahlgren and Myrhed, 1977;De Lint and Levinson, 1975;Finney and Moos, 1991;Gerdner and Berglund, 1997;Haver et al, 2009;Lambie et al, 1983;Lindberg and Agren, 1988;Liskow et al, 2000;Mackenzie et al, 1986;Marshall et al, 1994;Noda et al, 2001;Ohara et al, 1989;Ojesjo¨et al, 1998;Rossow and Amundsen, 1997;Schmidt and Popham, 1981;Smith et al, 1994;Thorarinsson, 1979;Vaillant, 2003;Wells and Walker, 1990). These studies showed that the observed mortality among alcoholics was approximately 2 to 5 times greater than expected; in some cases, the mortality excess among alcoholics was even greater (Finney and Moos, 1991;Gerdner and Berglund, 1997;Ohara et al, 1989).…”