Albumin versus crystalloid solutions in patients with the acute respiratory distress syndrome: a systematic review and meta-analysis

Uhlig, Christopher; Silva, Pedro L.; Deckert, Stefanie; Schmitt, Jochen; Abreu, Marcelo Gama de

doi:10.1186/cc13187

Cited by 87 publications

(61 citation statements)

References 29 publications

(48 reference statements)

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“…Since the 2012 SSC guideline publication, six systematic reviews/meta-analyses [237,[241][242][243][244][245] were published assessing the use of albumin solutions in the management of patients with sepsis or septic shock. Each meta-analysis included different populations (adult/child, septic/nonseptic, and acute resuscitation/maintenance), different comparators and different duration of exposure to the intervention (hours, days), which made combining data challenging (ESM 7).…”

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confidence: 99%

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

et al. 2017

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Objective: To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012". Design:A consensus committee of 55 international experts representing 25 international organizations was convened. Nominal groups were assembled at key international meetings (for those committee members attending the conference). A formal conflict-of-interest (COI) policy was developed at the onset of the process and enforced throughout. A stand-alone meeting was held for all panel members in December 2015. Teleconferences and electronic-based discussion among subgroups and among the entire committee served as an integral part of the development. Methods:The panel consisted of five sections: hemodynamics, infection, adjunctive therapies, metabolic, and ventilation. Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable.

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confidence: 99%

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

et al. 2017

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“…Mounting evidence shows that the right volume of fluid rather than the type of fluid is what ultimately improves mortality. 17,22,23 With the understanding of the glycocalyx becoming more elucidated, we may be getting closer to a game changer in fluid resuscitation strategy.…”

Section: Resultsmentioning

confidence: 99%

Glycocalyx in Sepsis Resuscitation

Chen

2016

Critical Care Nursing Quarterly

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Starling's forces are fundamental to our understanding of physiology. Based on his findings, hydrostatic pressure and oncotic pressure are crucial factors in the movement of intravascular and extravascular fluid. However, new literatures on endothelial glycocalyx, a layer of protective glycoprotein within the vasculature that was first discovered in the 1980s, are reshaping our standard models of Starling's forces. This article examines the nature of the endothelial glycocalyx and why understanding it may change the way we resuscitate patients with sepsis.

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“…Это связывали с тем, что гипоос-молярный (4%) раствор альбумина повышал интра-краниальное давление и отек головного мозга [25]. Вместе с тем применение 4% и 20% растворов ЧСА у 93 пострадавших с тяжелой черепно-мозговой трав-мой (шкала комы Глазго ≤ 8 баллов) при соблюдении нулевого или слабо отрицательного водного баланса обеспечивало низкую летальность у больных данной группы [26] и подтверждало необходимость исклю-чения из терапии гипоосмолярных растворов ЧСА.…”

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