1998
DOI: 10.1136/adc.79.5.384
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Albumin: saint or sinner?

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Cited by 33 publications
(14 citation statements)
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References 25 publications
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“…Although, there is controversy about the use of human albumin solution for volume replacement treatment,23 24 4.5% human albumin solution has been the main resuscitation fluid in meningococcal sepsis for several decades. In our experience of treating 425 children, the exclusive use of albumin has been associated with the lowest mortality yet for severe disease 10.…”
Section: Circulatory Supportmentioning
confidence: 99%
“…Although, there is controversy about the use of human albumin solution for volume replacement treatment,23 24 4.5% human albumin solution has been the main resuscitation fluid in meningococcal sepsis for several decades. In our experience of treating 425 children, the exclusive use of albumin has been associated with the lowest mortality yet for severe disease 10.…”
Section: Circulatory Supportmentioning
confidence: 99%
“…Haemodynamic improvement has been shown to persist for up to 36 hours (5). It is also noted that four times the volume of a crystalloid is required to obtain an equal volume enhancement.…”
Section: Colloid Osmotic Pressure Effectsmentioning
confidence: 97%
“…Já os cristalóides permanecem apenas 30 minutos no espaço intravascular (Nadel et al, 1998), podendo não reverter quadros de insuficiência circulatória aguda e desidratação grave. Mesmo assim, os cristalóides ainda são mais utilizados na clínica eqüina, principalmente por serem mais baratos (Griffel e Kaufman, 1992).…”
Section: Introductionunclassified
“…Embora alguns estudos estabeleçam uma relação inversa entre nível de albumina sérica e mortalidade ou demonstrem sua segurança (Human..., 1998;Nadel et al, 1998;Triulzi, 2003), há estudos que sugerem que sua utilização aumentaria o risco de morte em pacientes críticos (Human…, 1998). Mas, apesar da possibilidade de efeitos colaterais, o principal fator limitante ao uso de albumina em humanos é o custo (Roberts e Bratton, 1998).…”
Section: Introductionunclassified