Abstract:Therapeutic proteins, pivotal for treating diverse human
diseases
due to their biocompatibility and high selectivity, often face challenges
such as rapid serum clearance, enzymatic degradation, and immune responses.
To address these issues and enable prolonged therapeutic efficacy,
techniques to extend the serum half-life of therapeutic proteins are
crucial. The AlbuCatcher, a conjugate of human serum albumin (HSA)
and SpyCatcher, was proposed as a general technique to extend the
serum half-life of diverse the… Show more
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