ALBI Grade vs. Child-Pugh (CP) Score For Stratification Of Survival And Liver Function Decline In Patients With Hepatocellular Carcinoma (HCC) Treated With Radiotherapy (RT)

Mohiuddin, Jahan J.; Manjunath, Shwetha; Williams, G.R.; Grandhi, Nav; Xu, Han; Nadolski, G.; Hoteit, Maarouf; Karasic, Thomas B.; Hunt, S.J.; Prenner, Stacey; Ben‐Josef, Edgar; Wojcieszynski, Andrzej P.

doi:10.1016/j.ijrobp.2020.07.1814

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“…It can evaluate liver reserve function based on serum albumin and bilirubin levels. In recent years, researchers have found that ALBI grade can predict the prognosis of tumor patients, especially liver cancer patients ( 6 ). In the prognostic evaluation of GC patients, ALBI grade also plays an increasingly important role ( 7 ).…”

Section: Introductionmentioning

confidence: 99%

High albumin-bilirubin grade predicts worse short-term complications in gastric cancer patients with metabolic syndrome: a retrospective study

Luo,

Chen,

Chen

et al. 2023

J Gastrointest Oncol

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Background Preoperative albumin-bilirubin (ALBI) grade has been proposed and applied in recent years to evaluate the prognosis of liver cancer, but its role in gastric cancer (GC) is still unclear. This research aimed to examine the prognostic value of ALBI grade after gastrectomy among patients with GC complicated with metabolic syndrome (MetS). Methods There were 628 patients who received radical resection for GC. Laboratory data and short-term results were collected prospectively, and preoperative ALBI grades were calculated from the albumin and bilirubin levels. The appropriate ALBI cutoff value was calculated by receiver operating characteristic (ROC) curve analysis, which we used to put patients into high (>−2.54) and low (≤−2.54) ALBI grade groups. The differences between the short-term complication rates of the two groups were analyzed with the chi-square test. Results Of the included patients, 133 (21.2%) and 495 (78.8%) had high and low ALBI grades, respectively. A high ALBI grade (P=0.001), body mass index (BMI) ≥25 kg/m 2 (P=0.001), and hypertension (P=0.018) were independent risk factors for postoperative complications. In GC patients with and without MetS, the high ALBI subgroup showed more overall complications than the low ALBI subgroup (P=0.028 and P=0.001). Among GC patients with MetS, those with a high ALBI grade showed a higher incidence of serious complications than those with a low ALBI grade (P=0.001); a similar, nonsignificant trend occurred in non-MetS patients (P=0.153). Conclusions The preoperative ALBI grade is important in the prognosis of GC patients with MetS after gastrectomy. GC patients with MetS can lower their incidence of serious complications by adjusting their preoperative ALBI grade.

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Section: Introductionmentioning

confidence: 99%