Albendazole: a new therapeutic regimen in cutaneous larva migrans

Rizzitelli, G.; Scarabelli, G.; Veraldi, Stefano

doi:10.1046/j.1365-4362.1997.00263.x

Cited by 42 publications

(33 citation statements)

References 10 publications

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“…Two other treatments, oral albendazole (Rizzitelli et al 1997) and ivermectin (Caumes et al 1993), have reported efficacy for this condition although these were rarely used in our patients. There is little evidence to suggest the use of cryotherapy for this condition.…”

Section: Discussionmentioning

confidence: 79%

Outbreak of cutaneous larva migrans in a group of travellers

Tremblay

MacLean

Gyorkos

et al. 2000

Tropical Med Int Health

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Summary INTRODUCTION We describe an outbreak of cutaneous larva migrans (CLM) in a group of 140 holidaymakers to a resort in Barbados and the index case. METHODS A two-page questionnaire was mailed to holidaymakers and 90% responded. RESULTS 25.4% of respondents developed a rash consistent with CLM. Risk factors for developing the illness were younger age and less frequent use of protective footwear while walking to the beach. Patients had difficulty in obtaining a correct diagnosis during their initial medical consultation and in obtaining medication from pharmacies. Efficacious treatments were oral and topical thiabendazole. CONCLUSIONS CLM can occur in a large proportion of people exposed to contaminated soil or sand. Protective footwear is effective in reducing infection. Thiabendazole is an efficacious treatment.

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Section: Discussionmentioning

confidence: 79%

Outbreak of cutaneous larva migrans in a group of travellers

Tremblay

MacLean

Gyorkos

et al. 2000

Tropical Med Int Health

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“…Many subsequent reports testify to its efficacy (Coulaud et al, 1982;Williams and Monk, 1989;Jones et al, 1990;Sanguigni et al, 1990;Rizzitelli et al, 1997;Veraldi and Rizzitelli, 1999;Kim et al, 2002;You et al, 2002;Suh et al, 2003). Thus, we also adopted an albendazole approach to treat the described 3 cases at a dose of 400 mg once daily for 3-5 days.…”

Section: Discussionmentioning

confidence: 99%

Three clinical cases of cutaneous larva migrans

Kim¹,

Lee²,

Sohn

2006

Korean J Parasitol

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Three cases of cutaneous larva migrans (CLM) were diagnosed in a returnee from a trip to Thailand and in 2 domestic farmers during July and September, 2003. The linear and serpiginous skin lesions on the lower extremities were presented in all 3 cases. Routine laboratory findings were normal. In the imported case, a 650 x 30 µm sized filariform nematode larva, presumably a species of hookworm, was detected in the lesion. All cases were treated with 400 mg albendazole once daily for 3-5 days, and their skin lesions gradually improved. In the present study, a causative agent of CLM was isolated for the first time in the Republic of Korea. Moreover, we speculate that CLM is prevalent in farmers who are in frequent contact with soil in the Republic of Korea.

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“…CLM has been treated by physical modalities (freezing the skin with ethyl chloride or solid carbon dioxide), topical drugs, and systemic drugs (Kurgansky and Burnett, 1990). Albendazole has been shown to be effective in the treatment of CLM (Rizzitelli et al,1997). We report herein the two cases of CLM which were successfully treated with albendazole.…”

Section: Introductionmentioning

confidence: 95%