Alarming changes in the global burden of mental disorders in children and adolescents from 1990 to 2019: a systematic analysis for the Global Burden of Disease study

Piao, Jianmin; Huang, Yinqiong; Han, Cheng; Li, Yike; Xu, Yanbing; Liu, Yazhuo; He, Xue

doi:10.1007/s00787-022-02040-4

Cited by 48 publications

(50 citation statements)

References 35 publications

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“…The Cause of Death Ensemble model (CODEm), which serves as a versatile modeling program, can generate death estimates for all locations across the time series according to covariate data and geospatial linkages ( 13 ). Considering that not all diseases were assessed in some countries, DisMod-MR 2.1, a Bayesian meta-regression tool, was used in the GBD 2019 study as the primary estimation method to ensure the consistency between the incidence, prevalence, and mortality rates for each disease ( 14 ). Spatiotemporal Gaussian process regression (ST-GPR) is a collection of regression techniques that uses relationship analysis between different locations and periods to obtain specific metrics of interest, such as death rates or risk factor exposures.…”

Section: Methodsmentioning

confidence: 99%

Changes in the global, regional, and national burdens of NAFLD from 1990 to 2019: A systematic analysis of the global burden of disease study 2019

Wang

Zhu

et al. 2022

Front. Nutr.

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BackgroundUnderstanding the burdens and trends of non-alcoholic fatty liver disease (NAFLD) is necessary for developing effective intervention strategies. In this study, Global Burden of Disease (GBD) 2019 study data were extracted and analyzed to elucidate trends of NAFLD.MethodsThe prevalence, incidence, disability-adjusted life year (DALY), and death rates of NAFLD in geographic populations worldwide from 1990 to 2019 were extracted from the GBD 2019 study data. The global temporal trend of NAFLD from 1990 to 2019 was evaluated using estimated annual percentage changes (EAPCs) and age-standardized rates.ResultsGlobally, between 1999 and 2019, the age-standardized prevalence rate of NAFLD increased, with EAPCs of 0.77 [95% CI (0.69, 0.85)], whereas the DALY and Death rates decreased, with EAPCs of –0.82 [95% CI (–0.92, –0.71)], and –0.67 [95% CI (–0.76, –0.58)], respectively. Geographically, the age-standardized prevalence rate showed the most serious upward trend in high-income North America with an EAPC of 0.98 [95% CI (0.95, 1.02)], and the age-standardized incidence rate showed an upward trend in Central Asia with an EAPC of 3.17 [95% CI (2.2, 2.49)]. The most significant upward trend of DALY and death rates appeared in Eastern Europe, with EAPCs of 4.06 [95% CI (3.31, 4.82)], and 3.36 [95% CI (2.77, 3.96)], respectively. At the country level, the age-standardized rates showed an upward trend in Armenia, Belarus, and Republic of Korea. Regarding age groups, the percentage change of prevalence was the highest in the 40 to 44 group [0.29 (0.26, 0.34)] from 1990 to 2019; the percentage change of incidence was the highest in the 85 to 89 group [0.46 (0.12, 0.71)] from 1990 to 2019; the percentage change of DALY was the highest in the 80 to 84 group [0.25 (0.11, 0.39)] from 1990 to 2019; and the percentage change of death rate was the highest in the 15 to 19 group [0.36 (0.17, 0.60)] from 1990 to 2019. The percentage change of prevalence of liver cancer due to NASH was the highest in the group of 85 to 89, whereas those of incidence, DALY, and death were the highest in the group above 95 from 1990 to 2019. Regarding the sociodemographic index (SDI), the highest age-standardized prevalence, incidence, and Death rates of NAFLD occurred in middle-SDI countries, and the highest DALY rates of NAFLD occurred in low-SDI countries.ConclusionGlobal NAFLD burdens have increased since 1990. Our findings provide a reference for policymakers to reduce the burden of NAFLD, especially in middle and low-SDI countries.

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Section: Methodsmentioning

confidence: 99%

Changes in the global, regional, and national burdens of NAFLD from 1990 to 2019: A systematic analysis of the global burden of disease study 2019

Wang

Zhu

et al. 2022

Front. Nutr.

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“…From 1990 to 2019, the age-standardised rates of DALYs of mental disorders increased from 803.8 per 100 000 (95% CI: 567.7 to 1104.3 per 100 000) to 833.2 per 100 000 (95% CI: 589.0 to 1146.1 per 100 000) of children and adolescents. 6 Across the world, countries have made significant efforts to control the spread of SARS-CoV-2 through a variety of interventions including social distancing, mobility restrictions and school closures. Evidence from previous pandemics such as Ebola have demonstrated that these interventions may have unintended and harmful effects on the health of children and adolescents.…”

Section: What This Study Addsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Indirect effects of COVID-19 on child and adolescent mental health: an overview of systematic reviews

et al. 2022

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IntroductionTo control the spread of COVID-19, mitigation strategies have been implemented globally, which may have unintended harmful effects on child and adolescent mental health. This study aims to synthesise the indirect mental health impacts on children and adolescents globally due to COVID-19 mitigation strategies.MethodsWe included relevant reviews from MEDLINE, Embase, PsycINFO, LILACS, CINAHL, The Cochrane Library and Web of Science until January 2022 that examined the impact of COVID-19-related lockdown and stay-at-home measures on the mental health of children and adolescents. Data extraction and quality assessments were completed independently and in duplicate by BC and LH. A Measurement Tool to Assess Systematic Reviews-2 was used to assess the methodological quality.ResultsEighteen systematic reviews, comprising 366 primary studies, found a pooled prevalence of 32% for depression (95% CI: 27 to 38, n=161 673) and 32% for anxiety (95% CI: 27 to 37, n=143 928) in children and adolescents globally following COVID-19 mitigation measures. Subgroup analyses also uncovered important differences for both depression and anxiety by World Health Organization regions with few studies from Africa and relative high burden of anxiety and depression in the Eastern Mediterranean region.ConclusionsOur findings reveal a high prevalence of depression and anxiety in children and adolescents during the COVID-19 pandemic, globally, compared with prepandemic estimates. These findings highlight the urgency for governments and policymakers to strengthen mental health systems in the COVID-19 recovery, especially in low-and middle-income countries where compounding psychological stress, access and affordability of care and discrepant reporting of mental health in this population remains a challenge. We also provide insight into how to alter mitigation strategies to reduce the unintended negative consequences for the health and well-being of children and adolescents in future pandemics.PROSPERO registration numberCRD42022309348.

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“…This month sees the publication of an interesting paper from J Piao and colleagues [ 5 ] with secondary analyses from the Global Burden of Disease data including data on disease (including mental health disorders) from 1/01/1990 to 31/12/2019 for 204 countries, territories, and selected subnational locations. The authors focus on the prevalence, incidence, disability-adjusted life-years (DALYs), years of life lost (YLLs), and years lived with disability (YLDs) across 12 mental health disorders, including eating disorders, in children and adolescents < 20 years old in 1990 and 2019.…”

mentioning

confidence: 99%

“…Findings on the burden of ED in the article by Piao and colleagues [ 5 ] are striking. ED were the only mental health disorder associated with mortality in children and adolescents.…”

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confidence: 99%

What’s weighing us down: closing the gap between the global burden of eating disorders and their representation

Micali

2022

Eur Child Adolesc Psychiatry

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Alarming changes in the global burden of mental disorders in children and adolescents from 1990 to 2019: a systematic analysis for the Global Burden of Disease study

Cited by 48 publications

References 35 publications

Changes in the global, regional, and national burdens of NAFLD from 1990 to 2019: A systematic analysis of the global burden of disease study 2019

Changes in the global, regional, and national burdens of NAFLD from 1990 to 2019: A systematic analysis of the global burden of disease study 2019

Indirect effects of COVID-19 on child and adolescent mental health: an overview of systematic reviews

What’s weighing us down: closing the gap between the global burden of eating disorders and their representation

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