Alarm symptoms, risk factors for digestive tract cancer and readiness to participate in an endoscopic screening program

Ziółkowski, Bartłomiej; Pacholec, Agnieszka; Muszyński, J

doi:10.5114/pg.2013.34836

Cited by 2 publications

(1 citation statement)

References 35 publications

(34 reference statements)

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“…In one Polish study, only 169 of 850 (20%) patients with various gastrointestinal symptoms agreed to undergo gastroscopy. The respective percentage was higher, but still relatively low (62%), in patients with alarming symptoms [16]. As even the risk of malignancy does not prompt patients to accept screening tests, the response rate of 20% found in our study performed in busy area might not be as low as it seems at the first glance.…”

Section: Discussioncontrasting

confidence: 66%

Public Spirometry Campaign in Chronic Obstructive Pulmonary Disease Screening–Hope or Hype?

Korczyński

Górska

Jankowski

et al. 2017

Advances in Respiratory Medicine

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Section: Discussioncontrasting

confidence: 66%

Public Spirometry Campaign in Chronic Obstructive Pulmonary Disease Screening–Hope or Hype?

Korczyński

Górska

Jankowski

et al. 2017

Advances in Respiratory Medicine

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Assessment of the response to gluten-free diet in an Iraqi population with coeliac disease. A histological and serological follow-up study

Osman¹,

Taha²,

Duboni³

2014

aoms

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IntroductionCoeliac disease (CD) is a common diagnosis among children and adults in Iraq; however, removal of gluten from the diet is essential for patients with CD. The aim of this study, the first such study in Iraq, was to assess the serological and histological recovery profiles of coeliac patients, in both children and adults groups after commencing a gluten-free diet (GFD) for at least 1 year ± 1 month.Material and methodsThe study group comprised 78 proved coeliac patients (46 children and 32 adults, median age: 15 years, range: 1–66 years) who all agreed to undergo endoscopy in addition to serological assessment before and after treatment. The duodenal biopsies were interpreted histologically according to modified Marsh criteria and the sera were tested for anti-gliadin antibody (AGA), endomysium antibody (EMA) and anti-tissue transglutaminase antibody (tTG).ResultsComplete histological remission was seen in 29 (63.1%) of 46 treated children CD patients, while only 5 (10.9%) showed Marsh IIIa changes compared with 11 (24%) before GFD. Similarly none of the 32 adults after GFD showed Marsh IIIb and Marsh IIIc compared with 46.9% and 28.1% before treatment respectively (p = 001). Meanwhile, there was strongly significant reduction in AGA, EMA, and tTG antibodies levels (p = 0.00001) following GFD.ConclusionsRepeating the duodenal biopsy 1 year ±1 month after diagnosis and starting a GFD supports the routine measurement of using histological findings as a gold standard test to confirm recovery of Iraqi CD patients along with using known coeliac serology antibodies.

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Alarm symptoms, risk factors for digestive tract cancer and readiness to participate in an endoscopic screening program

Cited by 2 publications

References 35 publications

Public Spirometry Campaign in Chronic Obstructive Pulmonary Disease Screening–Hope or Hype?

Public Spirometry Campaign in Chronic Obstructive Pulmonary Disease Screening–Hope or Hype?

Assessment of the response to gluten-free diet in an Iraqi population with coeliac disease. A histological and serological follow-up study

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