Akute Exazerbation einer chronischen CLL mit multiplen pathologischen Frakturen

Abstract

Chronic lymphatic leukaemia (CLL) is one of the most common leukaemic diseases in middle Europe. Pathological fractures are rare findings in patients with CLL. The diagnosis of CLL is in most cases an incidental finding as it often stays asymptomatic for years. This article presents an interesting case of a 65-year-old male patient with known asymptomatic CLL for 5 years and fractures of the proximal femur and proximal radius after trauma. During the hospital stay the patient suffered multiple pathological fractures with histological findings of bony infiltration of the CLL and an acute phase, which was treated by combination chemotherapy.

Diagnosing a hematopoietic malignancy during shoulder arthroplasty: A case report

“…Incidental biopsies resulting in CLL diagnosis have also been reported in tissue samples from the lungs, oral cavity, and orbital sinus [12][13][14] . Extremity involvement is exceedingly rare, where reported cases were diagnosed with biopsies following pathologic fractures of the proximal femur and radius 15 . In rare cases, patients present with shoulder pain can have underlying lymphoma.…”