Aktuelle Kenntnisse zu Therapie und Prävention der kaninen Leishmaniose

Apostolopoulos, Neoklis; Mitropoulou, Athanasia; Thom, Nina; Moritz, Andreas

doi:10.15654/tpk-180089

Cited by 6 publications

(2 citation statements)

References 60 publications

(76 reference statements)

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“…Since this disease is a vector disease, vector control is also mandatory ( 40 , 41 ). Investigation of the Kızılırmak delta, located in this region where the study was carried out, in terms of vector screening is mandatory for the prevention of the disease.…”

Section: Discussionmentioning

confidence: 99%

Molecular Detectıon of Canine Leishmaniasis in Northern Anatolia, Turkiye

Yucesan,

Ozkan,

Tuncer

et al. 2023

IJPA

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Background: Canin leishmaniasis (CanL), mostly caused by Leishmania infantum, is one of the most important vector-borne diseases in dogs in the Mediterranean region. In this study, we aimed to determine the disease profile in this region by firstly making microscopic and then molecular analyzes in the samples taken from the dogs. Methods: Overall, 112 whole blood samples taken from dogs for clinical applications by a veterinarian in Cankırı between December 2021 and November 2022 were used. After blood collection, both thin and thick drop blood smear preparations were prepared and evaluated for Giemsa staining. L. infantum was investigated by Real time-PCR (RT-PCR) method from all blood samples. Sequence analysis and phylogenetic tree study were performed on positive samples. Results: Both microscopic and RT-PCR analyzes were performed. In both studies, 3 of the 112 samples were positive. Because of the sequence analysis, they were L. infantum. Sequence analysis was performed from the samples found 3 positive. The phylogenetic tree was drawn by making NCBI (National Center for Biotechnology) data entries of the positive samples (Accession numbers: OQ184728, OQ184729, OQ184730). Conclusion: Dogs are important, as they are reservoir of this disease. In this study, 3 (2.7%) positive Leishmaniasis was detected in dogs in Cankırı. Ultimately, this should prompt discussion about new strategies going forward to combat infection caused by Leishmania.

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Section: Discussionmentioning

confidence: 99%

Molecular Detectıon of Canine Leishmaniasis in Northern Anatolia, Turkiye

Yucesan,

Ozkan,

Tuncer

et al. 2023

IJPA

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“…This modelling could be extrapolated to the expansion of L. infantum , as well as to its vector. In fact, L. infantum has been detected not only in sandflies but also in dogs and horses of cold European countries [ 15 , 66 , 67 ], and scientists already recommend including cutaneous leishmaniasis in the differential diagnosis in human patients [ 68 ].…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Factors Related to Leishmania infantum Infection in Healthy Horses (Equus caballus) from Eastern Spain

Martínez-Sáez,

Dulac,

Montaner-Angoiti

et al. 2023

Animals

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Leishmaniosis is a zoonosis caused by Leishmania spp., an intracellular protozoan parasite. This parasite is transmitted by sandflies, and the disease is endemic in the Mediterranean basin. In recent years, the number of species which could be a reservoir of the parasite is increased. One of the most relevant species is the horse, due to their contact with humans and ability to control the disease, thus being a possible silent reservoir. In this study, we have analyzed the prevalence and factors related to L. infantum infection in healthy horses in the Mediterranean region. Epidemiological data and serum samples were obtained from 167 apparently healthy horses, and the presence of L. infantum was evaluated via the ELISA method and real-time PCR. The results show 27.5% of prevalence and that the main factors related to infection are equine breed, morphotype, outdoor living, use, and season. In conclusion, the prevalence of L. infantum infection in apparently healthy horses from eastern Spain (Mediterranean basin) is elevated. To control this zoonosis, it would be advisable to carry out more studies on this and other species that could be silent reservoirs of the parasite, as well as carry out measures such as the use of repellents on a regular basis.

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