Akne Vulgaris Dewasa : Etiologi, Patogenesis Dan Tatalaksana Terkini

Teresa, Astrid

doi:10.37304/jkupr.v8i1.1500

Cited by 5 publications

(5 citation statements)

References 36 publications

(42 reference statements)

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“…The primary causes of AV include excessive keratinocyte proliferation forming comedones, increased sebum production triggered by androgens, heightened inflammatory response, and the proliferation of P. acnes. 18,19 Acne begins with the overgrowth of skin cells (keratinocytes) within hair follicles. This overgrowth can lead to the formation of comedones (blackheads and whiteheads).…”

Section: Resultsmentioning

confidence: 99%

The relationship between menstrual cycle and psychological stress on acne vulgaris incidence

K P Dewi,

Munirah B,

Rahman H

2024

ACTA Medical Health Sciences

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Acne vulgaris (AV) is a chronic inflammation of the pilosebaceous unit and presents with a polymorphic clinical picture such as comedones, papules, pustules, nodules, and scars. AV is often experienced by both women and men, affecting 85% of young adults aged 12-25 years, with women more commonly affected than men. There are several triggers that contribute to the onset of AV, including the menstrual cycle and psychological stress. This study aims to determine the relationship between the menstrual cycle, psychological stress, and the occurrence of acne vulgaris in female medical students at Universitas Jenderal Achmad Yani. The research design uses a cross-sectional study approach. There were 48 people who met the inclusion criteria. Respondents in this study were asked to fill out informed consent forms, questionnaires, and indicate their availability for standardized facial photos. The results of this study obtained a p-value of 1.000 and 0.529 (p-value > 0.05). It was found that there is no statistically significant association observed between either regular menstrual cycles or severe psychological stress and the presence of acne vulgaris in this sample. The odds ratios for both variables (1.052 and 1.303) suggest minor increases in the odds of acne vulgaris presence, but they do not reach statistical significance. This relates to the occurrence of acne vulgaris, which is not only caused by factors such as the menstrual cycle and psychological stress but also by various triggering factors including diet, use of cosmetics, facial hygiene, and unhealthy sleep patterns.

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Section: Resultsmentioning

confidence: 99%

The relationship between menstrual cycle and psychological stress on acne vulgaris incidence

K P Dewi,

Munirah B,

Rahman H

2024

ACTA Medical Health Sciences

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“…Kebiasaan merokok dan paparan asap rokok dapat meningkatkan terjadinya acne vulgaris serta keparahannya. Paparan sinar matahari dapat menyebabkan munculnya acne vulgaris karena radiasi sinar ultra violet menyebabkan peroksidasi yang komedogenik dan reaksi inflamasi (Teresa, 2020).…”

Section: Pendahuluanunclassified

Efektivitas Penggunaan Zinc Pada Acne Vulgaris: Literature Review

Dibintang Akbari,

Pramuningtyas

2024

JCS

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Latar Belakang: Acne vulgaris (AV) merupakan penyakit inflamasi kronis pada unit kelenjar sebum dengan gambaran klinis berupa komedo, papula, pustula, nodul, dan jaringan parut. Penggunaan zinc pada acne vulgaris diduga memiliki kemampuan untuk memodulasi proses peradangan di kulit, menghambat proses kemotaksis leukosit di lesi acne, sintesis RBP, dan untuk menekan produksi sebum melalui efek anti-androgen. Tujuan: Penelitian ini dilakukan untuk mengetahui efektivitas penggunaan zinc pada acne vulgaris. Metode: Penelitian ini ditulis sebagai suatu literature review dengan metode analisis naratif menggunakan database meliputi PubMed, ScienceDirect, Google Scholar dengan menggunakan kata kunci (“Zinc”) AND (“Acne Vulgaris”). Kriteria Retriksi yaitu artikel penelitian tanpa batasan tahun, berbahasa Inggris ataupun Indonesia, desain studi kuantitatif, dan artikel penelitian yang membahas zinc dan acne vulgaris. Hasil : Jurnal yang diperoleh melalui 3 database sebanyak 1279 judul. Setelah melakukan screening, diperoleh 15 artikel yang sesuai kriteria restriksi. Hasil penelitian menunjukkan sebagian besar penggunaan zinc pada acne vulgaris memiliki efektivitas pada perbaikan baik acne vulgaris derajat ringan, sedang maupun berat. Efek penggunaan zinc mulai terlihat rata-rata pada minggu ke-6 hingga minggu ke-12. Kesimpulan : Bahwa penggunaan zinc pada acne vulgaris memiliki manfaat untuk penyembuhan acne vulgaris.

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“…Penyebab utama akne belum diketahui secara pasti, namun terdapat beberapa faktor yang berperan penting dalam patogenesis akne, salah satunya adalah hormon androgen. 1 Hormon androgen akan meningkat pada masa pubertas yang nantinya akan menstimulasi kelenjar sebasea, produksi sebum serta proliferasi folikel keratinosit. Androgen yang akan berinteraksi dengan androgen reseptor, yaitu testosteron (T) dan dihidrotestosteron (DHT).…”

Section: Pendahuluanunclassified

Effectiveness of Spironolactone for Acne Vulgaris

Wijaya,

Widodo,

Sanfika

2023

JMedScie

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Acne vulgaris is a skin disease that attacks pilosebaceous follicles which can be either inflammatory or non-inflammatory lesion. One of the important factors causing acne vulgaris is androgen hormone. One of the hormonal therapies that can be given for acne vulgaris is spironolactone which has a function as an antiandrogen. The purpose of writing this literature review is to determine the effectiveness, mode of action, indications, contraindications, and side effects of spironolactone in the treatment of acne vulgaris. The method in making this final project is Literature Review. Literature searches were obtained using electronic databases such as Google Scholar, PubMed, Proquest, International Journal of Women's Dermatology, and NCBI. The keywords used were spironolactone, hormonal therapy, acne vulgaris, effectiveness of spironolactone for acne vulgaris. There are 10 supporting journals based on the suitability of topics in the last 10 years. The results showed that the administration of spironolactone for acne vulgaris proved to be effective with an average dose of 50-100 mg/day which resulted in 70-90% clinical improvement and caused minimal side effects. Spironolactone has good effectiveness and tolerability for alternative therapy of acne vulgaris in adult women and for patients who do not respond well to conventional therapy.

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Akne Vulgaris Dewasa : Etiologi, Patogenesis Dan Tatalaksana Terkini

Cited by 5 publications

References 36 publications

The relationship between menstrual cycle and psychological stress on acne vulgaris incidence

The relationship between menstrual cycle and psychological stress on acne vulgaris incidence

Efektivitas Penggunaan Zinc Pada Acne Vulgaris: Literature Review

Effectiveness of Spironolactone for Acne Vulgaris

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