“…In total, thirty eight articles were included in the study and two of these studies compared the metabolism changes and genome variation in T. otitidis isolated from two sources (ear and blood). Out of 36 articles, 52.7% (19 articles) were case studies (Table 1 ) and 47.2% (17 articles) were retrospective studies (Table 2 ) [ 1 – 4 , 8 – 39 ]. Of the total studies, 81.5% of the articles were in English, while 18.4% were in NEL.…”
Section: Resultsmentioning
confidence: 99%
“…Additionally, the utilization of amoxicillin, fosfomycin, penicillin, rifampin, gentamycin, cefotaxime, and ciprofloxacin was reported in 41.7% of the cases. These antibiotics were administered either as monotherapy or given in combination [ 1 – 4 , 8 – 39 ]. Fig.…”
Section: Resultsmentioning
confidence: 99%
“… Author & year Age & sex Condition Source of isolation Method of identification Treatment 1 Mastroianni, A., et al, 2023 [ 40 ] 11-year old, male Acute lymphoblastic leukemia with acute or chronic otitis, mastoiditis, sinusitis Central venous catheter (CVC) blood Direct microscopy, Vitek2-Vitek MS Intravenous rifampicin, vancomycin CVC lock therapy, and CVC removal 2 Priyadarshini, S.R., et al,2021 [ 36 ] 10-year-old, male Microbial keratitis Corneal graft VITEK® 2 automated system Topical gatifloxacin 0.5% eye-drops 3 Koumaki, D., et al, 2020 [ 33 ] 74-year-old, female Palmoplantar eczema Skin VITEK® 2 automated system and biochemicals Cefuroxime 4 Mammo, D.A., D. Watson, and K.R. Armbrust,2020 [ 26 ] 71-year-old, male Neovascular age-related macular degeneration Endophthalmitis PCR NS 5 Li, D., et al, 2019 [ 11 ] 69-year-old, female Diffuse large B cell lymphoma, fever Blood MALDI-TOF MS Vancomycin 6 De Frutos, M., et al, 2018 [ 39 ] 46-year-old male Right otalgia with suppuration Right ear Pure culture Oral and topical ciprofloxacin …”
Section: Resultsmentioning
confidence: 99%
“… Author and year Age Sample size No. of Turicella otitidis cases or percentage Condition Source of isolation Identification 1 Gavrilovici, C., et al, 2022 [ 9 ] 2 months-7 years 147 n = 1 Acute otitis media Pus MICROSCAN panels (PC42, HIND) and MALDI-TOF MS NA 2 Mendez-Legaza, J.M., et al,2021 [ 23 ] 0–14 years and 2–81 years 1089 samples n = 22 ear exudate External auditory canal Culture, API Coryne, MALDI-TOF MS 3 Chen, T.Y., et al 2021 [ 20 ] NS 107 culturable isolates n = 10 Otitis media Middle ear sample NS 4 Álvarez, A.S. and M.G. Coca, 2021 [ 32 ] NS 273 ear exudates n = 18 Acute otitis media Middle ear fluid samples ANC card of the Vitek2® system 5 Barron, C.L., et al, 2020 [ 19 ] 9 months- 19 years 38 effusion n = 1 Chronic middle ear effusions Middle ear fluid Culture, Immunoblot (DNABII proteins) …”
Turicella otitidis belongs to the Corynebacteriaceae family and is a normal inhabitant of the ear and exists in a commensal relationship with its host. In children, T. otitidis is frequently associated with otitis media. The emergence of Turicella otitidis as a pathogen is concerning, particularly due to the limited availability of data on its pathogenic properties. The objective of this study is to conduct a systematic review of T. otitidis infections occurring in both the ear and other anatomical sites, and to summarize the differences in metabolism and genome sequences between isolates obtained from the ear and blood.
“…In total, thirty eight articles were included in the study and two of these studies compared the metabolism changes and genome variation in T. otitidis isolated from two sources (ear and blood). Out of 36 articles, 52.7% (19 articles) were case studies (Table 1 ) and 47.2% (17 articles) were retrospective studies (Table 2 ) [ 1 – 4 , 8 – 39 ]. Of the total studies, 81.5% of the articles were in English, while 18.4% were in NEL.…”
Section: Resultsmentioning
confidence: 99%
“…Additionally, the utilization of amoxicillin, fosfomycin, penicillin, rifampin, gentamycin, cefotaxime, and ciprofloxacin was reported in 41.7% of the cases. These antibiotics were administered either as monotherapy or given in combination [ 1 – 4 , 8 – 39 ]. Fig.…”
Section: Resultsmentioning
confidence: 99%
“… Author & year Age & sex Condition Source of isolation Method of identification Treatment 1 Mastroianni, A., et al, 2023 [ 40 ] 11-year old, male Acute lymphoblastic leukemia with acute or chronic otitis, mastoiditis, sinusitis Central venous catheter (CVC) blood Direct microscopy, Vitek2-Vitek MS Intravenous rifampicin, vancomycin CVC lock therapy, and CVC removal 2 Priyadarshini, S.R., et al,2021 [ 36 ] 10-year-old, male Microbial keratitis Corneal graft VITEK® 2 automated system Topical gatifloxacin 0.5% eye-drops 3 Koumaki, D., et al, 2020 [ 33 ] 74-year-old, female Palmoplantar eczema Skin VITEK® 2 automated system and biochemicals Cefuroxime 4 Mammo, D.A., D. Watson, and K.R. Armbrust,2020 [ 26 ] 71-year-old, male Neovascular age-related macular degeneration Endophthalmitis PCR NS 5 Li, D., et al, 2019 [ 11 ] 69-year-old, female Diffuse large B cell lymphoma, fever Blood MALDI-TOF MS Vancomycin 6 De Frutos, M., et al, 2018 [ 39 ] 46-year-old male Right otalgia with suppuration Right ear Pure culture Oral and topical ciprofloxacin …”
Section: Resultsmentioning
confidence: 99%
“… Author and year Age Sample size No. of Turicella otitidis cases or percentage Condition Source of isolation Identification 1 Gavrilovici, C., et al, 2022 [ 9 ] 2 months-7 years 147 n = 1 Acute otitis media Pus MICROSCAN panels (PC42, HIND) and MALDI-TOF MS NA 2 Mendez-Legaza, J.M., et al,2021 [ 23 ] 0–14 years and 2–81 years 1089 samples n = 22 ear exudate External auditory canal Culture, API Coryne, MALDI-TOF MS 3 Chen, T.Y., et al 2021 [ 20 ] NS 107 culturable isolates n = 10 Otitis media Middle ear sample NS 4 Álvarez, A.S. and M.G. Coca, 2021 [ 32 ] NS 273 ear exudates n = 18 Acute otitis media Middle ear fluid samples ANC card of the Vitek2® system 5 Barron, C.L., et al, 2020 [ 19 ] 9 months- 19 years 38 effusion n = 1 Chronic middle ear effusions Middle ear fluid Culture, Immunoblot (DNABII proteins) …”
Turicella otitidis belongs to the Corynebacteriaceae family and is a normal inhabitant of the ear and exists in a commensal relationship with its host. In children, T. otitidis is frequently associated with otitis media. The emergence of Turicella otitidis as a pathogen is concerning, particularly due to the limited availability of data on its pathogenic properties. The objective of this study is to conduct a systematic review of T. otitidis infections occurring in both the ear and other anatomical sites, and to summarize the differences in metabolism and genome sequences between isolates obtained from the ear and blood.
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