Aislamiento de Mycobacterium lentiflavum en un caso sospechoso de cáncer de pulmón

Mycobacterium lentiflavum, an emerging pathogen?

“…The cases involving the respiratory apparatus are limited to two tuberculosis-like infections in elderly patients 3,10 and to one isolation, whose significance is, however questionable, from a patient with doubtful diagnosis. 6 The present isolations from pleural fluids seems to fulfill the ATS criteria as the strains were grown from an otherwise sterile district and no other possible responsible of disease was detected. 14 Furthermore, both patients clearly benefited by antimycobacterial treatment.…”

“…4 Likewise other non-tuberculous mycobacteria (NTM), M. lentiflavum may infect humans and may even be responsible of disease, both in HIV-positive 3,5 and -negative subjects. [1][2][3][6][7][8][9][10] According to the reports of the literature the neck lymphadenitis of children is the most frequent pathology due to this organism. 3,9,[11][12][13] We report here, along with a further case of cervical lymphadenopathy in a young boy, the first isolations from pleural fluid in a young patient with leukaemia and in an elderly man.…”

Cutaneous Infection by <i>Mycobacterium lentiflavum</i> in a Patient with HIV

“…One child with lymphadenitis was treated with rifampin and isoniazid, and another child was treated with rifampin and clarithromycin and lymph nodes were also excised. One case of an adult patient with pleural effusion was treated successfully with isoniazid, rifabutin, ethambutol and pyrazinamide for 4 months [8] . Optimal chemotherapy has not been established for infections with M. lentiflavum .…”