Airway symptoms and sleeping difficulties in operated and non-operated patients with gastroesophageal reflux disease

Johannessen, Rune; Petersen, H; Olberg, Petter; Johnsen, Gjermund; Fjøsne, U.; Kleveland, P. M.

doi:10.3109/00365521.2012.683041

Cited by 8 publications

(4 citation statements)

References 29 publications

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“…In a systematic review, laparoscopic fundoplication significantly improved QOL scores and symptoms for at least 1 year [147]. Moreover, airway symptoms and sleeping difficulties associated with GERD symptoms [148], acid reflux in esophageal impedance-pH monitoring [149,150], intestinal metaplasia in Barrett's esophagus on endoscopy [149], and bile reflux [150] were also significantly improved by laparoscopic fundoplication compared to medication.…”

Section: (4) Enteric Infectionmentioning

confidence: 99%

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

et al. 2016

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As an increase in gastroesophageal reflux disease (GERD) has been reported in Japan, and public interest in GERD has been increasing, the Japanese Society of Gastroenterology published the Evidence-based Clinical Practice Guidelines for GERD (1st edition) in 2009. Six years have passed since its publication, and there have been a large number of reports in Japan concerning the epidemiology, pathophysiology, treatment, and Barrett's esophagus during this period. By incorporating the contents of these reports, the guidelines were completely revised, and a new edition was published in October 2015. The revised edition consists of eight items: epidemiology, pathophysiology, diagnosis, internal treatment, surgical treatment, esophagitis after surgery of the upper gastrointestinal tract, extraesophageal symptoms, and Barrett's esophagus. This paper summarizes these guidelines, particularly the parts related to the treatment for GERD. In the present revision, aggressive proton pump inhibitor (PPI) maintenance therapy is recommended for severe erosive GERD, and on-demand therapy or continuous maintenance therapy is recommended for mild erosive GERD or PPI-responsive non-erosive GERD. Moreover, PPI-resistant GERD (insufficient symptomatic improvement and/or esophageal mucosal break persisting despite the administration of PPI at a standard dose for 8 weeks) is defined, and a standard-dose PPI twice a day, change in PPI, change in the PPI timing of dosing, addition of a prokinetic drug, addition of rikkunshito (traditional Japanese herbal medicine), and addition of histamine H2-receptor antagonist are recommended for its treatment. If no improvement is observed even after these treatments, pathophysiological evaluation with esophageal impedancepH monitoring or esophageal manometry at an expert facility for diseases of the esophagus is recommended.

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Section: (4) Enteric Infectionmentioning

confidence: 99%

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

et al. 2016

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“…Several studies compared surgery with conservative treatment [21][22][23]. Surgeries are more effective than medical therapy.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

et al. 2021

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Background and Objectives: Gastroesophageal reflux disease (GERD) is one of the most common gastrointestinal diseases. It affects 20% of the adult population and is the third most common cause of chronic cough in adults. This study describes the results of LNF for the relief of GERD-related cough. Materials and Methods: The prospectively collected data on 135 laparoscopic LNF in our department from 2014 to 2018 were reviewed. During consultations, patients were asked about the frequency of symptoms using the GERD Impact Scale (GERD-IS), their satisfaction and recommendation to others, and their general condition after the procedure. Results: We analyzed 23 of 111 patients (20.7%) reporting chronic cough. The mean age was 47 years (range 27–76 years, ±13.9 years) and the mean follow-up time was 48.3 months (range 22.6–76.3 ± 18.05 months). Most patients reported relief from cough after the surgery (78.3%, p < 0.001). Five patients (22%) reported the recurrence of symptoms after a mean of 10.8 months (6–18 months). Seventeen patients (74%) would undergo the surgery again and 18 patients (78%) would recommend the surgery to their relatives. There was a statistically significant improvement in all symptoms from the GERD-IS (p < 0.05). Conclusions: LNF may play an important role in the management of GERD patients with extraesophageal symptoms. After LNF, most of the operated patients reported complete resolution of chronic cough and would recommend the procedure to their relatives.

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“…Johannessen et al performed a retrospective matched cross‐sectional study of 179 patients with GERD who underwent antireflux surgery, matched to 179 similar patients who were treated medically. On the Reflux, Airway, and Sleep Questionnaire, the median score for globus sensation, sore throat, and the laryngopharyngitis subscale of the questionnaire were significantly lower in the antireflux surgery group (0.76, 0.86, and 1.06, respectively) than in the medically treated group (1.11, 1.13, and 1.27, respectively) [44]. Swoger et al followed ten patients prospectively with presumed LPR who underwent laparoscopic Nissen and compared them to 15 unmatched controls that declined surgery and continued twice a day PPI therapy.…”

Section: Effect Of Antireflux Surgery Laryngopharyngeal Refluxmentioning

confidence: 99%

Surgical Treatment of Extraesophageal Manifestations of Gastroesophageal Reflux Disease

et al. 2017

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Extraesophageal manifestations of GERD are common, costly, and difficult to treat. ARS might be effective in highly selected patients, especially in those whose extraesophageal manifestations are caused by non-acid reflux. The available data to date are generally of poor quality or outdated. Well-designed randomized controlled trials or large-scale observational cohort studies are urgently needed.

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Airway symptoms and sleeping difficulties in operated and non-operated patients with gastroesophageal reflux disease

Abstract: Patients operated for GERD have less heartburn/acid regurgitation symptoms and less airway symptoms than non-operated patients. The findings lend support to the hypothesis of a causal relationship between gastroesophageal reflux, airway symptoms, and sleeping difficulties.

Cited by 8 publications

References 29 publications

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

Evidence-based clinical practice guidelines for gastroesophageal reflux disease 2015

Long-Term Outcomes of Chronic Cough Reduction after Laparoscopic Nissen Fundoplication—A Single-Center Study

Surgical Treatment of Extraesophageal Manifestations of Gastroesophageal Reflux Disease

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