Airway reflux, cough and respiratory disease

Abstract

It is increasingly accepted that the effects of gastro-oesophageal reflux are not limited to the gastrointestinal tract. The adjacent respiratory structures are also at risk from material ejected from the proximal oesophagus as a result of the failure of anatomical and physiological barriers. There is evidence of the influence of reflux on several respiratory and otorhinological conditions and although in many cases the precise mechanism has yet to be elucidated, the association alone opens potential novel avenues of therapy to clinicians struggling to treat patients with apparently intractable respiratory complaints. This review provides a description of the airway reflux syndrome, its effects on the lung and current and future therapeutic options.

Laryngopharyngeal Reflux Disease in War-torn Syria and its Association with Smoking and other Risks.

“…This correlation did not exist with shisha in our study. Moreover, GORD was found to be correlated with respiratory diseases and asthma (19) which is similar to our ndings for LPR.…”

Evaluation of Antibiotic Prescription for Upper Respiratory Tract Infections in the Community Pharmacy Setting

“…Despite the absence of allergic and GERD patients in our sample, the relationship between these conditions and URTI has been noticed by other authors [4,5] . However, an information bias must be considered because there could have been a misinterpretation or misunderstanding regarding the questions made during the interview.…”

Evaluation of Antibiotic Prescription for Upper Respiratory Tract Infections in the Community Pharmacy Setting

“…Despite the absence of allergic and GERD patients in our sample, the relationship between these conditions and URTI has been noticed by other authors [4,5] . However, an information bias must be considered because there could have been a misinterpretation or misunderstanding regarding the questions made during the interview.…”