Airway Pathogens During the First Year after Lung Transplantation: A Single-Center Experience

Microbiological findings in bronchoalveolar lavage fluid from lung transplant patients in Sweden

“…The low prevalence of MDR bacteria in our study reflects that Sweden still has a favorable situation regarding antimicrobial resistance compared to most countries. In comparison, Kovatz et al described a MRSA prevalence of 25% in lung transplant patients in the first post‐operative year, and Tebano et al found MDR strains in respiratory samples in 90 of 179 lung transplanted patients (51%). In a recent publication, Rodrigo‐Troyano et al describes the serious threat posed by Gram‐negative MDR bacteria in respiratory infections.…”

Invasive Fungal Infections in Solid Organ Transplant Recipients

“…When infection does occur, it is usually as bloodstream infection and is much less common than pleural space infection or other forms of invasive disease [51]. Candida species are frequently found in respiratory samples from lung transplant recipients and donors [52]. These are rarely clinically relevant, although transmission of Candida from a donor lung has been reported, with resultant pulmonary, peritoneal and bloodstream involvement in the recipient [14].…”

Isolation of Aspergillus species from the airway of lung transplant recipients is associated with excess mortality

“…Previous studies have found similar rates of between 31 and 50%. 3,6,7,10 Typically, isolation of Aspergillus spp. occurs early in the post-operative course.…”

“…are found in at least 50% of lung transplant patients in the first year following transplantation. 10 Colonisation or IPA most commonly occurs in the first three months following lung transplantation, but may occur as late as three years. 3 In the first six months following lung transplantation patients with Aspergillus colonisation are eleven times more likely to acquire IPA.…”