Airway Management of the Critically Ill Patient<sup>*</sup>

Reynolds, Stuart F.; Heffner, John E.

doi:10.1378/chest.127.4.1397

Cited by 109 publications

(84 citation statements)

References 109 publications

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“…Etomidate is widely used in trauma patients as a single bolus for tracheal intubation. There are many advantages to using etomidate in this population, including a short duration of action with few cardiovascular side effects [2]. Despite these attractive characteristics, we observed an increased rate of HAP in etomidate-exposed patients.…”

Section: Discussionmentioning

confidence: 56%

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Etomidate increases susceptibility to pneumonia in trauma patients

Asehnoune

Mahé²,

Séguin

et al. 2012

Intensive Care Med

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Section: Discussionmentioning

confidence: 56%

“…Etomidate has a favourable haemodynamic profile and is frequently used as a single bolus for rapid sequence intubation [1,2]. However, the use of etomidate remains controversial in critically ill patients [3].…”

Section: Introductionmentioning

confidence: 99%

Etomidate increases susceptibility to pneumonia in trauma patients

Asehnoune

Mahé²,

Séguin

et al. 2012

Intensive Care Med

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“…17 In adult and pediatric emergency room and intensive care units, 'rapid-sequence intubations' using neuromuscular-blocking agents are more common. 18,19 Studies have shown increased rates of success 20,21 and decreased rates of complications 22 in intubations performed after administration of neuromuscular paralysis in pediatric and adult patients. Several prospective investigations in the neonatal population have reported similar favorable results.…”

Section: Common Practicesmentioning

confidence: 99%

Rocuronium for nonemergent intubation of term and preterm infants

et al. 2010

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Objective: The aim of this study was to analyze clinical characteristics of rocuronium as premedication for nonemergent intubation in infants.Study Design: Preterm infants requiring nonemergent intubation were randomized to receive atropine and fentanyl with or without rocuronium. Outcomes, patient characteristics and intubator's experience were noted. Onset, duration and degree of clinical paralysis were recorded for rocuronium group and for older infants receiving rocuronium per unit protocol.Result: Forty-four intubations were randomized (20 rocuronium, 24 control). Groups were similar in chronological and corrected gestational age, weight and intubator's experience. Successful intubation on first attempt was achieved in 35% of intubations under rocuronium vs 8% of controls; rocuronium was the only significant variable by logistic regression (odds ratio ¼ 0.052, P ¼ 0.029). Complete paralysis was reported in 80% of 57 rocuronium intubations; onset ranged from 14 to 178 s (65.9±43.4), and duration from 1 to 60 min (16.3 ± 13.5).Conclusion: Rocuronium facilitated successful intubation and provided clinical paralysis quickly in most infants.

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“…Applying CPAP during preoxygenation has been suggested to optimize preoxygenation in critically ill patients, on the assumption that CPAP will increase the FRC of the lung. 5 However, Cressey et al 6 demonstrated no prolongation in the time to desaturate to 90% following preoxygenation with 7.5 cm H 2 O CPAP with 100% oxygen when compared with standard preoxygenation in apneic morbidly obese women. Further, Cressey et al 6 postulated that the effectiveness of CPAP in their study could have been enhanced by higher CPAP levels since increased CPAP may further expand the FRC.…”

Section: Discussionmentioning

confidence: 99%