Airway Management in Patients with Robin Sequence

Han, Kevin; Seruya, Mitchel; Preciado, Diego; Oh, Albert K.

doi:10.1007/978-3-642-30770-6_11

Cited by 2 publications

(3 citation statements)

References 47 publications

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“…The literature on PRS is still scarce, and there are few studies describing individuals with PRS from a multidisciplinary perspective. Management of patients with PRS is still controversial and often differs significantly across teams and treatment centers (Han et al, 2013).…”

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confidence: 99%

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Filip

Feragen²,

Lemvik³

et al. 2015

The Cleft Palate-Craniofacial Journal

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Even though the mean weight percentile for newborns with Pierre Robin sequence was low, the patients did not show a growth spurt during the first year of life. The high rate of velopharyngeal insufficiency after cleft palate repair in patients with Pierre Robin sequence needs further investigation. Also, the high rate of autism spectrum disorder among boys with Pierre Robin sequence prompts further investigation.

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mentioning

confidence: 99%

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Filip

Feragen²,

Lemvik³

et al. 2015

The Cleft Palate-Craniofacial Journal

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“…18 Patients were then classified into 2 groups, based upon presence or absence of FTT at the time of the initial PSG. Maximum end tidal carbon dioxide (ETCO 2 ), AHI, O 2 saturation nadir, and time of O 2 saturation <90% were used as proxy variables from the PSG to quantify the severity of sleep apnea, based on previous data from our institution 19,20…”

Section: Methodsmentioning

confidence: 99%

“…Patients were then classified into 2 groups, based upon presence or absence of FTT at the time of the initial PSG. Maximum end tidal carbon dioxide (ETCO 2 ), AHI, O 2 saturation nadir, and time of O 2 saturation <90% were used as proxy variables from the PSG to quantify the severity of sleep apnea, based on previous data from our institution 19,20 that showed these 4 factors, termed the MIST criteria, to be associated with failure of prolonged conservative management; specifically, maximum ETCO 2 >62 mm Hg, AHI >23 events/hour, O 2 saturation nadir <79.4%, and time of O 2 saturation <90% of greater than 5.7% (Supplementary Digital Content, Table 1, http://links.lww.com/SCS/C593).…”

Section: Methodsmentioning

confidence: 99%

Severity of Airway Obstruction May Not Correlate With Weight Gain or Failure to Thrive in Infants With Robin Sequence: A Pilot Study

Mantilla-Rivas

Rana

Bryant

et al. 2021

Journal of Craniofacial Surgery

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Objective: Patients with Robin sequence (RS) can present with varying degrees of upper airway obstruction, difficulty maintaining adequate weight gain, and failure to thrive (FTT). Although inductive reasoning would suggest that these issues should be interrelated, the relationships between these factors have not been formally studied. This investigation explores the correlation between polysomnographic (PSG) findings, weight gain, and FTT in patients with RS. Design: A prospective database for baseline PSG parameters and serial weight measurements in infants with RS who were admitted for airway obstruction was reviewed. The association between PSG variables and calorie intake with FTT was assessed using univariate and multivariable logistic regression. Categorical analysis of the PSG variables against FTT was explored with a Poisson regression, and linear regression was performed to evaluate the correlation between PSG parameters and percentage of weight gain. Results: Univariate and multivariate logistic regression in RS patients with (n ¼ 13) and without (n ¼ 20) FTT showed no significant association between apnea-hypopnea index (adjusted odds ratio [aOR]: 0.99, P-value ¼ 0.403), O 2 nadir (aOR: 0.98, P-value ¼ 0.577), time of O 2 saturation below 90% (aOR: 1.03, P-value ¼ 0.574), maximum end tidal carbon dioxide (aOR: 1.0, P-value ¼ 0.977), and average calorie intake (OR:1.02; P-value ¼ 0.984). Furthermore, no significant associations were identified between these variables and weight gain. Conclusions: This pilot study questions the widely held and intuitively logical belief that poor weight gain and/or FTT should correlate with the severity of upper airway obstruction in patients with RS. Large prospective investigations should be initiated to better explore the authors' findings. Our results also underscore the importance of individualized treatment for these challenging patients.

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Airway Management in Patients with Robin Sequence

Cited by 2 publications

References 47 publications

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Multidisciplinary Aspects of 104 Patients with Pierre Robin Sequence

Severity of Airway Obstruction May Not Correlate With Weight Gain or Failure to Thrive in Infants With Robin Sequence: A Pilot Study

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