Abstract:In this paper, recent reviews of the World Health Organization, other review papers, and more recent literature on the human health effects of current air pollution trends in urban areas are reviewed and summarized as follows: Sulphur dioxide. Some studies, but not others, found associations between sulphur dioxide (SO2) exposure and daily mortality and morbidity. Single-pollutant correlations sometimes disappeared when other pollutants, especially suspended particulate matter (SPM), were included. Cross-secti… Show more
“…Among smokers matched for daily tobacco consumption there are marked variations of the amount of carbon monoxide hemoglobin (2,21). To what extent this may be accounted for by air pollution (22), brand of tobacco, use of filter, inhalation habits and time since last smoked cigarette remains to be evaluated. It can be concluded, however, that cardiovascular risk estimates based solely on the number of cigarettes smoked per day are improved by levels of CO in blood or expired air.…”
Methods: Three hundred and sixty-five men without history of cardiovascular disease (CVD) were followed over 27 years. Leg artery disease was defined as a systolic anklearm pressure ratio (ABPI) below 0.9 in either leg. Incidence of myocardial infarction (MI), stroke and deaths is based on linkage with regional and national registers. The distribution of CO in blood and expired air, respectively, was divided into quartiles.Results: There was a significant inverse relation between ABPI and CO in blood and expired air. Incidence of CVD events and deaths increased progressively with degree of CO exposure. Men with CO in the top quartile had significantly increased risks of CVD events (RR: 2.2; 95% CI: 1.00-4.6) and cardiovascular deaths (RR: 3.2, CI: 1.2-8.3), adjusted for daily tobacco consumption and other potential confounders.
Conclusions:In smokers, the prevalence of leg atherosclerosis and incidence of cardiovascular disease is related to the amount of carbon monoxide in blood or expired air.
“…Among smokers matched for daily tobacco consumption there are marked variations of the amount of carbon monoxide hemoglobin (2,21). To what extent this may be accounted for by air pollution (22), brand of tobacco, use of filter, inhalation habits and time since last smoked cigarette remains to be evaluated. It can be concluded, however, that cardiovascular risk estimates based solely on the number of cigarettes smoked per day are improved by levels of CO in blood or expired air.…”
Methods: Three hundred and sixty-five men without history of cardiovascular disease (CVD) were followed over 27 years. Leg artery disease was defined as a systolic anklearm pressure ratio (ABPI) below 0.9 in either leg. Incidence of myocardial infarction (MI), stroke and deaths is based on linkage with regional and national registers. The distribution of CO in blood and expired air, respectively, was divided into quartiles.Results: There was a significant inverse relation between ABPI and CO in blood and expired air. Incidence of CVD events and deaths increased progressively with degree of CO exposure. Men with CO in the top quartile had significantly increased risks of CVD events (RR: 2.2; 95% CI: 1.00-4.6) and cardiovascular deaths (RR: 3.2, CI: 1.2-8.3), adjusted for daily tobacco consumption and other potential confounders.
Conclusions:In smokers, the prevalence of leg atherosclerosis and incidence of cardiovascular disease is related to the amount of carbon monoxide in blood or expired air.
“…A relationship between ambient air pollution and daily mortality and morbidity rates has been reported for many cities throughout the world (Schwela, 2000;Stieb et al, 2002;Glinianaia et al, 2004;Gordon et al, 2004). The relevant contaminants include sulfur dioxide, suspended particulate matter, nitrogen dioxide, carbon monoxide, ozone, and lead (Schwela, 2000).…”
Section: Ambient Air Exposure Pathwaymentioning
confidence: 93%
“…There is a consistent body of evidence that exposure to ambient air pollution is associated with increased respiratory symptoms of cough, bronchitis, respiratory infection, and upper respiratory tract illness in children (Dockery et al, 1989;Raizenne et al, 1996;Schwela, 2000). Although the effects of pollutants appear small, they occur at levels within the national ambient air quality standards of most countries and have the potential to affect large populations of children.…”
Section: ) Ambient Airmentioning
confidence: 99%
“…The relevant contaminants include sulfur dioxide, suspended particulate matter, nitrogen dioxide, carbon monoxide, ozone, and lead (Schwela, 2000). Ambient air pollution has been declared an important health problem for developing countries.…”
The urinary metabolites of phthalates are well-accepted exposure biomarkers for adults and children older than 6 years but are not commonly used for infants owing to non-convenient sampling. In the light of this situation, a novel sampling method based on monitoring the urine expressed from the gel diaper was developed. The urine was expressed from the gel absorbent after mixing the absorbent with CaCl2 and then collected by a laboratory-made device; the urinary phthalate metabolites were extracted and cleaned using a solid-phase extraction (SPE) column and analyzed with high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry / mass spectrometry. To evaluate the method's feasibility, the following factors were investigated: the proportion of CaCl2 to gel absorbent, the urination volume variation and the target compounds' deposition bias in the diaper, the matrix blank of the different diaper brands, the storage stabilities and the recoveries of creatinine and phthalate metabolites in the expressed urine. Mono-methyl phthalate, mono-ethyl phthalate, mono-butyl phthalate, mono-benzyl phthalate, mono-2-ethylhexyl phthalate and mono-2-ethyl-5-oxohexyl phthalate were involved. 70-80% of the urine can be expressed from the diaper, and the expressed spiking recoveries and the limit of detection of mono-phthalates ranged from 88.5-115% and 0.21-0.50 ng/ml. The method was applied to measure phthalate metabolites in 65 gel diaper samples from 15 infants, and the pilot data suggests the infants are commonly exposed to phthalates. In summary, the method for monitoring of infant exposure to phthalates is sound and validated, and the potential health effects from the vulnerable infants' exposure to phthalates should be concerned.39th Scientific Research Foundation for the Returned Overseas Chinese Scholars (SRF for ROCS); Hundred Talent Program of Chinese Academy of Sciences (CAS); CAS/SAFEA International Partnership Program for Creative Research Teams [KZCX2-YW-T08
“…Frying fumes have also irritating content such as aldehydes, aerosols, and VOCs (Svendsen et al 2003), some of which are mutagenic substances (Sjaastad and Svendsen 2008). PM have been linked to pulmonary, cardiac, renal, and dermal toxic effects (Schwela 2000).…”
Indoor air quality has a great impact on human health. Cooking, in particular frying, is one of the most important sources of indoor air pollution. Indoor air CO, CO 2 , particulate matter (PM), and volatile organic compound (VOC) concentrations, including aldehydes, were measured in the kitchen of a small establishment where a special deepfrying margarine was used. The objective was to assess occupational exposure concentrations for cooks of such restaurants. While individual VOC and PM 2.5 concentrations were measured before, during, and after frying events using active sampling, TVOC, PM 10 , CO, CO 2 , temperature, and relative humidity were continuously monitored through the whole period. VOC and aldehyde concentrations did not increase to considerable levels with deep-frying compared to the background and public indoor environment levels, whereas PM 10 increased significantly (1.85 to 6.6 folds). The average PM 2.5 concentration of the whole period ranged between 76 and 249 μg/m 3 . Hence, considerable PM exposures could occur during deep-frying with the special margarine, which might be sufficiently high to cause health effects on cooks considering their chronic occupational exposures.
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