Air Pollution and Cardiovascular Disease

Emmerechts, Jan; Jacobs, Lotte; Hoylaerts, Marc

doi:10.5772/21587

Cited by 6 publications

(2 citation statements)

References 127 publications

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“…However, the link between environment variations with VTE is less established than to arterial thrombotic events, however, the air pollutants negatively act on several targets (leukocyte, platelets, coagulative factors, inflammatory markers and endothelial markers) which play crucial roles in pathophysiology of the VTE and DVT. We agree with the conclusive remarks given by Emmerechts et al (45) who considered the exposure to air pollutants as the highest risk factors for thrombotic events. Therefore, there is a need to reduce such exposure both at individual and global level.…”

Section: Discussionsupporting

confidence: 93%

Deep vein thrombosis related to environment

Signorelli

Ferrante

Gaudio

et al. 2017

Molecular Medicine Reports

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The first-time venous thromboembolism (VTE) is less frequent than other thrombotic events, however, both the pulmonary embolism (PE) and the deep vein thrombosis (DVT) show a frequent morbidity. Many factors play as risk situations in determining VTE, and the air exposure to the fine and ultrafine particulate matter (PM) as PM10, PM2.5, PM0.1 is considered. Epidemiological studies have supported this association although both the effective burden of the association and the mechanisms are to date unclear. The PM concentrations and the exposure time are notable as emerging factors. Interestingly, the seasonal climate variations resulted as effective risk factor for appearance of VTE or DVT. There is a need to ameliorate the environment by reducing the air pollution at global scale.

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Section: Discussionsupporting

confidence: 93%

Deep vein thrombosis related to environment

Signorelli

Ferrante

Gaudio

et al. 2017

Molecular Medicine Reports

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“…There is a significant relationship between air pollutants and various diseases, including cancer, asthma, allergies, RDs, and CDs. This relationship has been well-documented in scientific literature (77)(78)(79)(80)(81)(82)(83). The effects of air pollution exposure on the heart and lungs are illustrated in Figure 5.…”

Section: Air Pollution and Cardiovascular And Respiratory Diseasesmentioning

confidence: 55%

Effect of COVID-19 and Air Pollution on the Risk Factors Attributed to COPD, Cardiovascular, and Respiratory Diseases

Nikmanesh,

Zarea,

Hatamzadeh

et al. 2023

Jundishapur J Chronic Dis Care

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Context: A wide range of complications, including chronic respiratory diseases, asthma attacks, cardiovascular diseases (CDs), various cancers (blood, lung, and brain), and even death, can result from air pollution. It is essential to assess the health effects on humans caused by environmental air pollutants and non-communicable diseases (NCDs), including coronavirus disease 2019 (COVID-19). The purpose of this review study was to investigate the synergistic effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and air pollutants on the risk factors for chronic obstructive pulmonary disease (COPD), CDs, and respiratory diseases (RDs). Evidence Acquisition: An extensive literature review was conducted. A total of 1 005 articles were retrieved from sources, including Google Scholar, Springer, PubMed, Web of Science, and Springer databases. In the final stage of the literature review, a significant association between mortality related to COVID-19 and air pollution emissions was identified, contributing to the risk factors associated with CDs and RDs. Results: The result showed that air pollution can have synergistic effects on the transmission of SARS-CoV-2 viruses and has an increasing effect on the incidence of RDs [such as SARS and Middle East respiratory syndrome (MERS)] and CDs. According to the findings, exposure to toxic air pollutants, whether chronic or acute, can have severe effects, including a decrease in airway ciliary function, damage to the mucous membrane, reduced air sac elasticity, decreased lung capacity, and an increased risk of CDs. Conclusions: COVID-19 and air pollutants pose a serious threat to human and animal health. Epidemiological studies have shown that in addition to environmental conditions, individual sensitivity plays a key role in the development of conditions such as COPD, CDs, RDs, cancer, and mortality.

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