Air Embolism and Other Accidents Using Pump Oxygenators

Stoney, William S.; Alford, William C.; Burrus, George R.; Glassford, David M.; Thomas, Chantal

doi:10.1016/s0003-4975(10)61481-6

Cited by 135 publications

(59 citation statements)

References 7 publications

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“…6 Victims of air embolism occurring as a result of submarine escape training immediately receive hyperbaric treatment. Pressure produces an immediate relief of symptoms in most cases, but approximately 20% of victims with initial recovery will later develop increasing headache, visual changes, and worsening of the original focal deficit.…”

mentioning

confidence: 99%

Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.

Dutka

Mink

McDermott

et al. 1992

Stroke

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Background and Purpose: Victims of air embolism often recover rapidly on hyperbaric treatment then deteriorate again, even if hyperbaric treatment is continued. In previous animal experiments, lidocaine has been shown to improve recovery of somatosensory evoked response amplitude after air embolism. However, animals in these experiments rarely deteriorated. We have shown that the induction of air embolism and transient hypertension in canines produces deterioration despite hyperbaric treatment, and we decided to test the effect of lidocaine on somatosensory evoked potential recovery and cerebral blood flow in this model.Methods: Dogs were treated with repeated doses of lidocaine or equivalent volumes of saline during hyperbaric therapy after internal carotid air embolism and transient hypertension. The investigators were unaware of treatment group assignment during the experiments. The amplitude of the median nerve somatosensory evoked potential and cerebral blood flow measured with carbon-14-labeled iodoantipyrine autoradiography were used to assess effect of therapy.Results: Lidocaine-treated dogs recovered 60±10% (mean±95% confidence limits) of the baseline somatosensory evoked potential amplitude 220 minutes after air embolism; saline-treated dogs recovered 32±10% (a significant difference atp<0.01). Lidocaine-treated dogs also had higher cerebral blood flow values than saline-treated dogs 220 minutes after air embolism.Conclusions: Lidocaine ameliorated the delayed deterioration of evoked potential associated with air embolism and hypertension in this canine model. The improved cerebral blood flow may be a mechanism of action of lidocaine or an associated effect of improved neuronal survival. (Stroke 1992;23:1515-1521 KEY WORDS • cerebral blood flow • embolism • evoked potentials, somatosensory • lidocaine • dogs

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mentioning

confidence: 99%

Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.

Dutka

Mink

McDermott

et al. 1992

Stroke

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“…When incidence rates were calculated from the respondents' total caseload experience, gas embolism occurred once every 8000 cases in the current survey versus once every 2500 cases in the 1980 survey by Stoney et ale [3]. This decreased incidence may be due to the fact that more perfusionists use a low-level alarm (70% now versus 42% earlier).…”

Section: Discussionmentioning

confidence: 69%

Cerebral Protection during Cardiopulmonary Bypass: Devices and Techniques to Prevent Air Embolism

Kurusz

Conti

1990

Impact of Cardiac Surgery on the Quality of Life

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“…Of the three most commonly cited surveys, the first was performed by Stoney et al 2 tor failure, and the occurrence of permanent injury or death.…”

Section: Cpb Complication Surveysmentioning

confidence: 99%

“…There have been, to date, three large retrospective studies conducted by questionnaire, asking physicians or perfusionists about common accidents that occur during CPB. [2][3][4] Even though the incidence of perfusion accidents is quite small, ranging from 0.3070 to 1 % (Table 18.1), in an effort to decrease the risk ofCPB there has been much discussion about prevention strategies by the authors of these outcome studies and others. In addition, every perfusionist should be prepared to deal quickly and efficiently with any potential accident or error.…”

Section: Introductionmentioning

confidence: 99%

Safety and Management of Perturbations During Cardiopulmonary Bypass

Sadel¹

1995

Cardiopulmonary Bypass

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Air Embolism and Other Accidents Using Pump Oxygenators

Cited by 135 publications

References 7 publications

Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.

Effect of lidocaine on somatosensory evoked response and cerebral blood flow after canine cerebral air embolism.

Cerebral Protection during Cardiopulmonary Bypass: Devices and Techniques to Prevent Air Embolism

Safety and Management of Perturbations During Cardiopulmonary Bypass

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