AIPH‐Encapsulated Thermo‐Sensitive Liposomes for Synergistic Microwave Ablation and Oxygen‐Independent Dynamic Therapy (Adv. Healthcare Mater. 17/2023)

Abstract

MICROWAVE ABLATION2 , 2 ' -A z o b i s ( 2 -[ 2 -i m i d a z o l i n -2 -y l ] p r o p a n e ) dihydrochloride (AIPH)-loaded temperaturesensitive liposomes can be well accumulated in the tumor site after intravenous injection. In article 2202947 by Hu Peng, Zhengbao Zha, and co-workers, when the tumor is exposed to the environment of microwave thermal ablation, the liposomes release the loaded AIPH and the AIPH decomposes to produce cytotoxic free radicals. Tumor growth is effectively inhibited through the synergy of hyperthermia and thermodynamic therapy.