AIDS-Related Bronchogenic Carcinoma

Epidemiologia do câncer do pulmão

“…Ainda não está definido se a infecção pelo HIV aumenta a probabilidade de o paciente vir a sofrer de câncer do pulmão. Mas o trabalho de Parker et al sugere que os indivíduos infectados pelo HIV têm risco 6 ½ vezes maior de desenvolver câncer do pulmão do que a população não infectada (53) .…”

Cancer incidence in women with or at risk for HIV

“…5 In 1993, invasive cervical cancer (ICC) was added to the case definition of AIDS 5 on the basis of increased incidence of precancerous lesions in HIV-infected women; 6,7 however, although excess cases of ICC have been reported, to our knowledge no statistically significant increased incidence of cervical cancer in HIV-infected women has yet been demonstrated, especially in a cohort. 8 -11 Other cancers such as Hodgkin's disease, lung cancer and nonmelanomatous skin cancer have been suggested to be HIV-related, 6,12,13 but supporting data are based on studies in primarily male populations, and results have been inconsistent. 14,15 In addition, HIV serostatus is usually not known but is assumed to be negative in historic controls, making it difficult to develop firm conclusions about the difference in incidence between infected and uninfected persons.…”

“…14,15 In addition, HIV serostatus is usually not known but is assumed to be negative in historic controls, making it difficult to develop firm conclusions about the difference in incidence between infected and uninfected persons. 16 -18 In studies matching AIDS case registry with cancer registry data, 7,12,13 results vary by study and region. Although the occurrence of AIDS-defining cancers is consistent across the studies, other cancers do not occur with consistency, indicating that there are most likely other factors contributing to an increase in a particular cancer in a given population; also, as with studies using historic controls, the number of women in such reports remains relatively small.…”

Uveal metastatic carcinoma in human immunodeficiency virus infection

“…9 However, other non-AIDS defining tumors, such as lung cancer, have increased in frequency in patients with HIV. 3,4 Recent studies have suggested that lung cancers are more aggressive in HIV patients; it usually occurs at a younger age, and there is a shorter survival time. 3,9 Why are there not then additional case reports of metastatic uveal carcinoma in HIV infection in the literature?…”

“…This is surprising given the reported increased incidence of lung carcinoma in patients with HIV infection. 3,4 We report two cases of metastatic choroidal carcinoma in patients with HIV infection.…”