Agrochemicals Induced Gene Expression Alterations in O.MOSSAMBICUS.

Pandya, Parth; Parikh, Pragna

doi:10.21474/ijar01/743

Cited by 3 publications

(1 citation statement)

References 16 publications

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“…In addition, the half‐life of PE has been observed in the near‐aquatic environment by agricultural runoff (Singh & Singh, 2011). In line with this, previous studies performed by our group (Pandya & Parikh, 2016; Pandya et al., 2018; Upadhyay et al., 2014) have provided deeper insights into neuroendocrine toxicity at the expression level (gene and protein) and general biochemical alterations. Oreochromis mossambicus was selected as the test model due to its abundance in the freshwaters of India and its sturdiness (Moyle et al., 2010).…”

Section: Introductionsupporting

confidence: 74%

Herbicide pyrazosulfuron ethyl induces genotoxicity, cell cycle alterations and apoptosis in tilapia (Oreochromis mossambicus)

Upadhyay

Pandya²,

Salunke

et al. 2022

Aquaculture Fish & Fisheries

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Fishes are excellent subjects for the study of the mutagenic and carcinogenic potential of contaminants present in water. Herbicides are one of the toxic contaminants that cause lethal effects in fish. In this context, the present study was designed to study the sub‐lethal toxic effect (low dose [LD] 25 mg/L, medium dose‐50 mg/L, and high dose [HD] 100 mg/L) of a commonly used herbicide, pyrazosulfuron ethyl (PE), on erythrocytes of tilapia. The genotoxic effect was studied to understand the sub‐lethal potential by means of (a) the nuclear abnormalities, including the micronucleus (MN) frequency; (b) further, each stage of the cell cycle was analysed using flow cytometry and (c) finally, the targets of PE was deciphered using in silico analysis. The results showed that there were significant effects of time (7 and 14 days) and doses in the increase in the frequency of MN in erythrocytes of fish treated with PE, compared to the control group. After exposing fish to PE for 7 and 14 days, there was a proportional increase in the frequency of the apoptotic population of erythrocytes for LD to HD. During both time exposures (7 and 14 days), the highest cell death was accounted for in HD. Moreover, the majority of the cells showed a dysregulated cell cycle in the G1 phase in all the treated groups of PE, compared to the control group. This study showed that PE might initiate genotoxicity in non‐target species (tilapia) of the aquatic ecosystem near agricultural fields.

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Section: Introductionsupporting

confidence: 74%

Herbicide pyrazosulfuron ethyl induces genotoxicity, cell cycle alterations and apoptosis in tilapia (Oreochromis mossambicus)

Upadhyay

Pandya²,

Salunke

et al. 2022

Aquaculture Fish & Fisheries

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Potential biomarker of phenol toxicity in freshwater fish C. mrigala: Serum cortisol, enzyme acetylcholine esterase and survival organ gill

Muthukumaravel

Kanagavalli²,

Pradhoshini³

et al. 2023

Comparative Biochemistry and Physiology Part C: Toxicology &

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Documentation of Chitrakathi Paintings of Maharashtra and Its Product Development

Gogate

Chauhan

2021

Global Journal for Research Analysis

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The Indian art and design of unimaginable antiquity have over the millennia and up till present day, evinced a continuity that has survived every historical, socio-economical, and political development to produce an art that is specically Indian. Chitrakathi is an ancient tradition of Thakar tribe of Maharashtra In the time of urbanization and industrialization, Chitrakathi is ghting for its survival. The study was undertaken to understand in detail about origin and history, tools, process, motifs, colors, and present status of the painting. The researcher has made an attempt to create awareness and popularize the Chitrakathi paintings by the product development.

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Agrochemicals Induced Gene Expression Alterations in O.MOSSAMBICUS.

Cited by 3 publications

References 16 publications

Herbicide pyrazosulfuron ethyl induces genotoxicity, cell cycle alterations and apoptosis in tilapia (Oreochromis mossambicus)

Herbicide pyrazosulfuron ethyl induces genotoxicity, cell cycle alterations and apoptosis in tilapia (Oreochromis mossambicus)

Potential biomarker of phenol toxicity in freshwater fish C. mrigala: Serum cortisol, enzyme acetylcholine esterase and survival organ gill

Documentation of Chitrakathi Paintings of Maharashtra and Its Product Development

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