There is the growing belief that uncontrolled agricultural activities greatly reduce the quality of the environment wherein they are carried out, and in turn, this environmental degradation negatively affects agricultural sector performance as a whole. It is on the strength of this assertion that this paper examines the relationships between environmental quality (carbon dioxide emission) and agricultural sector performance (ASP) in Cameroon using the Vector Autoregressive modelling approach. Specifically, the paper attempts to determine whether environmental quality affects ASP or there is a reverse causation. Using time series data obtained from the 2018 version of the World Development Indicators from 1981 to 2016, the study reveals a negative and significant effect of the first lag of ASP on its current value while the first lag of environmental quality equally has a negative and significant influence on its current value in Cameroon over the study period. Further, there is a negative and significant effect of ASP on environmental degradation. The granger causality test shows that there is a bidirectional relationship between environmental quality and ASP in Cameroon. Finally agricultural labour negatively and significantly affects environmental degradation in Cameroon. From the findings of this study, it is recommended that the government should put in place policies that will promote agricultural produce transformation as well as preservation strategies. Also, farmers should practice farm fragmentation so as to reduce the chances of all the crops ripening at the same time. Afforestation policies should be fully implemented and agricultural development, extension and value chain strategies should be put in place. Restrictions and sanctions should be placed on initiators of bush fire and poor farming practices such as shifting cultivation and bush fallowing methods should be discouraged in favour of intensive farming through sensitization by agricultural extension services.