The sustainability and resilience of agrifood systems are key concepts to ensure environmental standards in agriculture and food security. Recently, global food security have been seriously affected by the pandemics, geopolitical issues, and conflicts, and climate change factors has become a significant concern to scientists together with farmers, consumers, and citizens. To face those challenges, a systemic resilience in sustainable agriculture is pivotal. The research papers published in the special section of the Agronomy Journal, entitled, “Agricultural and Biological Sciences: Plant, Soil, Animal and Environment” consider the role of sustainability in building greater resilience to current pivotal, diverse problems encountered in agricultural systems. The special section is a collection of coherent research studies that used a multidisciplinary approach. A total of 52 papers were submitted of which 12 were accepted for publication following a double‐blind reviewing process. The purposes of the present paper were to identify the role of sustainability in the resilience of agricultural systems and to discuss the main results of these published articles. Results suggested that specific issues relevant to forests, crops, horticulture systems and animal production could be improved and made more resilient by applying modern agricultural tools, efficient use of natural resources and smart device technology. A sustainable intensification in a changing environment will require resilience at many levels. Key strategies identified included: i) improvement of resource efficiency; ii) adoption of techniques that generate landscape‐scale resilience; iii) combination of different strategies in evaluation and planning across scales to advance the knowledge of crop and livestock interactions.This article is protected by copyright. All rights reserved