Agreement between the Multi-Beat Analysis algorithm for cardiac output estimation and 2D echocardiography in the ICU

Abstract

Background Cardiac output (CO) and stroke volume (SV) monitoring are cornerstones of hemodynamic management in patients at risk of shock. The multi-beat analysis (MBA) method provides continuous estimates of CO and SV by analysis of a patient’s arterial blood pressure waveform. In this study we assessed the agreement of CO and SV between 2D echocardiography (CO-ECHO and SV-ECHO) and the multi-beat analysis (MBA) method via the Argos monitor (CO-MON and SV-MON).Methods Fifty patients with a wide range of diagnoses were prospectively enrolled in the ICU in this observational, method comparison study. One set of paired, simultaneous measurements was recorded for each patient.Results for the 50 included data points in the study the mean difference between CO-ECHO and CO-MON was − 0.05 ± 0.58 L/min with limits of agreement from − 1.18 to + 1.08 L/min and a percentage error of 21.5%. The mean difference between SV-ECHO and SV-MON was − 0.9 ± 6.6 mL with limits of agreement from − 13.9 to + 12.0 mL and a percentage error of 22.8%.Conclusion Accuracy of the MBA method was clinically acceptable as compared to 2D echocardiography.