Agreement between colposcopy results using the Reid Colposcopic Index and histopathology

Abstract

Objectives: The aim of the study was to evaluate the diagnostic efficacy of colposcopy and to determine the strength of correlation between colposcopic impression using the Reid Colposcopic Index (RCI) and histopathology. Material and methods:

Closer to a Uniform Language in Colposcopy: Study on the Potential Application of 2011 International Federation for Cervical Pathology and Colposcopy Terminology in Clinical Practice

“…Further calculations of significant differences confirmed the superiority. In various reports over the past 30 years, the sensitivity, specificity, PPV, and NPV of the RCI were shown to be extremely variable [ 1 , 19 – 21 , 25 , 26 ], while the results of the modified RCI and Swede Score were roughly equal to ours [ 2 , 3 , 8 , 9 , 22 , 23 ]. A few studies have reported the colposcopic accuracy of the IFCPC classification.…”

“…As the most well-known scoring system, the RCI was first reported by Reid and Scalzi in 1985 [1] and was shown to have good consistency of strength kappa as 0.55–0.74 with histopathology in several reports [19–21, 25, 26]. However, with cervical screenings and typical colposcopic impressions of precancers becoming increasingly uncommon, the accuracy of colposcopy as the standard method has been questioned [4].…”

“…Our results indicate that the perfect agreement, agreement within one grade, and strength of consistency between colposcopic diagnosis and cervical histopathology in nomenclature trained colposcopists according to the 2011 classification were all better than those in colposcopists without nomenclature training according to the RCI, modified RCI, and Swede Score. As the most well-known scoring system, the RCI was first reported by Reid and Scalzi in 1985 [ 1 ] and was shown to have good consistency of strength kappa as 0.55–0.74 with histopathology in several reports [ 19 – 21 , 25 , 26 ]. However, with cervical screenings and typical colposcopic impressions of precancers becoming increasingly uncommon, the accuracy of colposcopy as the standard method has been questioned [ 4 ].…”

A phase 1/2a, dose-escalation, safety and preliminary efficacy study of oral therapeutic vaccine in subjects with cervical intraepithelial neoplasia 3

“…The RCI is one of the most verified colposcopic scoring system for evaluating the precancerous cervical lesions. According to the previous studies investigating correlation of RCI and CIN lesions, there was good correlation between RCI and histopathology [1516]. It consists of 4 colposcopic signs including color, vessels, margin, and iodine staging, and each sign is assigned between 0 and 2 according to colposcopic findings.…”

Comparison of Diagnostic Accuracy of Colposcopic Findings Using Modified Reid Colposcopic Index with Histopathology in Cervical Lesions

“…The main reason is lack of effective screening programmes which can detect and treat preliminary stage of this life threatening disease [3]. Cervical cancer has a long latent phase and can be easily prevented using early screening methods, including Pap smears, human papilloma virus (HPV) testing, cervical examination using acetic acid, Lugol's iodine and colposcopy [4,5].…”