Agrammatic comprehension caused by a glioma in the left frontal cortex

Kinno, Ryuta; Muragakı, Yoshihiro; Hori, Tomokatsu; Maruyama, Takashi; Kawamura, Mitsuru; Sakai, Katsuyuki

doi:10.1016/j.bandl.2009.05.001

Cited by 32 publications

(21 citation statements)

References 42 publications

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“…3E). These results are consistent with our previous results (Kinno et al, 2009) with better sensitivity, indicating that both of L. F3op/F3t and L. LPMC are sufficient to cause agrammatic comprehension.…”

Section: Vlsm Analyses For Gray and White Matterssupporting

confidence: 83%

“…According to correlation analyses, the error rates for each condition could not be attributed to their ages, verbal / nonverbal IQs, or tumor volumes and GM ratio (all, p > 0.1). These results corresponded with our previous findings (Kinno et al, 2009), demonstrating that the tumor locations affected the actual performance of the three main conditions. The RTs for the patients and the normal controls are also shown in …”

Section: Behavioral Analysessupporting

confidence: 82%

“…Approval for the experiments was obtained from the institutional review board of the University of Tokyo, Komaba. The patients in our previous study (Kinno et al, 2009), who were scanned with the same protocol of MRI in the present study, were all included. Date are shown as mean ± standard deviation MR images were normalized with SPM8 for determination of tumor location and volume (mm 3 ), as well as the ratio (%) of gray matter (GM) for each tumor.…”

Section: Participantsmentioning

confidence: 99%

“…In the fMRI study, we observed that activations in L. dF3t (extending to L. F3op) and L. LPMC were differentially modulated by these three main conditions. Moreover, we have recently found that a glioma in the opercular and triangular parts of the left inferior frontal gyrus (L. F3op/F3t) or left lateral premotor cortex (L. LPMC) is indeed sufficient to cause agrammatic comprehension that is selective to syntactic decision (Kinno et al, 2009). These findings indicated that our paradigm with three distinct syntactic conditions of AS, PS, and SS would be ideal for appropriately assessing agrammatic comprehension, because the same set of actions depicted by pictures was used under the main conditions, thus controlling semantic comprehension per se.…”

mentioning

confidence: 99%

See 3 more Smart Citations

Gray or White? – The Contribution of Gray Matter in a Glioma to Language Deficits

Kinno¹,

Muragakı²,

Sakai³

2011

Advances in the Biology, Imaging and Therapies for Glioblastoma

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Section: Vlsm Analyses For Gray and White Matterssupporting

confidence: 83%

Section: Behavioral Analysessupporting

confidence: 82%

Section: Participantsmentioning

confidence: 99%

mentioning

confidence: 99%

See 2 more Smart Citations

Gray or White? – The Contribution of Gray Matter in a Glioma to Language Deficits

Kinno¹,

Muragakı²,

Sakai³

2011

Advances in the Biology, Imaging and Therapies for Glioblastoma

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“…In linguistics, when competing theories possess identical explanatory powers, the possibility of language acquisition has been successfully used to constrain the range of theory (Chomsky, 1965; Yang, 2010). Moreover, agrammatism, which is a type of aphasia specific to syntactic processing, has been useful in clarifying domain-specific linguistic competence by dissociating domain-general components (Friedmann and Grodzinsky, 1997; Kinno et al, 2009). In a similar way, developmental and disability studies of the concept of intentionality may also help us to theorize the nature of the concept.…”

Section: Developmental and Disability Studiesmentioning

confidence: 99%

How (not) to draw philosophical implications from the cognitive nature of concepts: the case of intentionality

Iijima

Ota

2014

Front. Psychol.

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Philosophers have often appealed to intuitive judgments in various thought experiments to support or reject particular theses. Experimental philosophy is an emerging discipline that examines the cognitive nature of such intuitive judgments. In this paper, we assess the methodological and epistemological status of experimental philosophy. We focus on the Knobe effect, in which our intuitive judgment of the intentionality of an action seems to depend on the perceived moral status of that action. The debate on the philosophical implications of the Knobe effect has been framed in terms of the distinction between the competence and performance of the concept of intentionality. Some scholars seem to suggest that the Knobe effect reflects the competence (or otherwise, the performance error) of the concept of intentionality. However, we argue that these notions are purely functional and thus do not have philosophical implications, without assuming normativism, which we see as problematic in a psychological methodology. Finally, focusing on the gap between competence and rationality, we suggest future directions for experimental philosophy.

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Does a lesion in Broca's area cause apraxia?

Tsuruya

Kobayakawa

Futamura

et al. 2013

Neurology & Clinical Neurosc

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Background and Aim: Broca's area, which comprises the inferior frontal gyrus and its surrounding regions, is associated with language function. Recent functional imaging studies showed that it is also related to processing goal-directed actions.This study aimed to determine the types of action disorders that occur after damage to Broca's area. Methods: Here, we report four patients with left inferior frontal lesions that included Broca's area. The patients did not exhibit severe language comprehension impairment or paralysis that affected the apraxia testing. The patients were asked to perform intransitive gestures in response to verbal commands, imitate intransitive gestures, perform transitive gestures in response to verbal commands, perform transitive gestures in response to visual objects, imitate transitive gestures, and use tools. Results: All patients exhibited impaired gestures in response to verbal commands, while the performances regarding imitation and actual tool use were better. An error pattern analysis showed that the patients predominantly made spatial action errors. This pattern corresponds to the classical definitions of ideomotor apraxia. Conclusion: These results indicate that Broca's area mediates action production and that a lesion in this area can cause ideomotor apraxia. Although we should be cautious about the influence of aphasia, we believe that the comprehension deficit observed in our patients cannot account for their apraxic syndromes. Because the deficit was seen mainly for verbal commands, damage in Broca's area may have disrupted the association between verbal and action domains.

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Agrammatic comprehension caused by a glioma in the left frontal cortex

Cited by 32 publications

References 42 publications

Gray or White? – The Contribution of Gray Matter in a Glioma to Language Deficits

Gray or White? – The Contribution of Gray Matter in a Glioma to Language Deficits

How (not) to draw philosophical implications from the cognitive nature of concepts: the case of intentionality

Does a lesion in Broca's area cause apraxia?

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