AgNPs-incorporated nanofiber mats: Relationship between AgNPs size/content, silver release, cytotoxicity, and antibacterial activity

Lv, Huaxin; Cui, Sisi; Yang, Qiannan; Song, Xin; Wang, Duo; Hu, Junli; Zhou, Yifa; Liu, Yichun

doi:10.1016/j.msec.2020.111331

Cited by 60 publications

(23 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Besides, they can inhibit the activity of endocellular ATP levels, thereby preventing the cell's respiratory function. Furthermore, AgNPs have been reported to induce the release of reactive oxygen species (ROS), forming free radicals with strong bactericidal effects (Figure 5) [75]. AgNPs have a broad antibacterial spectrum covering aerobic, anaerobic, and Gram amphoteric bacteria [76], low incidence of resistance [77], and sustained antibacterial activity [78], thus have been widely used in antibacterial wound dressings [75].…”

Section: Antimicrobial Activities Of Ag Nanofibersmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial Effect of Electrospun Nanofibers Loaded with Silver Nanoparticles: Influence of Ag Incorporation Method

Villarreal-Gómez

Pérez-González

Bogdanchikova

et al. 2021

Journal of Nanomaterials

View full text Add to dashboard Cite

The antimicrobial bioactivity of silver nanoparticles is well known, and they can be used widely in many applications, becoming especially important in the biomedical industry. On the other hand, the electrospun nanofibers possess properties that can enhance silver nanoparticle applicability. However, silver nanoparticle bioactivity differs depending on the loading of silver ions into electrospun nanofibers. This review is aimed at comparing different silver incorporation methods into electrospun nanofibers and their antimicrobial activity, discussing each procedure’s limitations, and presenting the most promising one. This review showed that the preferred techniques for incorporating silver nanoparticles were direct blending and ultraviolet irradiation methods due to their simplicity and efficient results. Besides, polyacrylonitrile nanofibers (PAN) have been the most reported system loaded with silver nanoparticles. Finally, independently of the technique used, silver nanoparticle-loaded nanofibers show high antimicrobial activity in all cases.

show abstract

Section: Antimicrobial Activities Of Ag Nanofibersmentioning

confidence: 99%

“…Thus, AgNP toxicity correlates with size and content because of the Ag + initial release rate, affecting the fibrous scaffold cytotoxicity. However, the AgNP amount also regulates the long-term Ag + release rate and, therefore, the microbicidal activity [72,75].…”

Section: Antimicrobial Activities Of Ag Nanofibersmentioning

confidence: 99%

Antimicrobial Effect of Electrospun Nanofibers Loaded with Silver Nanoparticles: Influence of Ag Incorporation Method

Villarreal-Gómez

Pérez-González

Bogdanchikova

et al. 2021

Journal of Nanomaterials

View full text Add to dashboard Cite

show abstract

“…Lv et al fabricated starch/Ag nanoparticle (2.2–5.6 nm) nanofibers with a diameter of approximately 500 nm and evaluated their cytotoxicity to fibroblasts (L929 cells). [ 77 ] They found that the larger the Ag nanoparticles and the lower their content, the lower is the cytotoxicity. This is because the initial rapid release of Ag ions is dominant in the size of Ag nanoparticles and content.…”

Section: Biocompatibility Of 1d Nanomaterialsmentioning

confidence: 99%

Recent Advances in 1D Nanomaterial‐Based Bioelectronics for Healthcare Applications

Song

Kim

Lee

et al. 2021

Advanced NanoBiomed Research

View full text Add to dashboard Cite

Figure 1. Schematic illustration of various bioelectronic devices based on 1D nanomaterials including nanowire, nanotube, and nanofiber. a) Nanowire, nanotube, and nanofiber are the representative 1D nanomaterials. b) Cellular scale bioelectronics based on 1D nanomaterials for cell signal recording and stimulation. Nanowire array to monitor signal of cell: Reproduced with permission. [93] Copyright 2017, American Chemical Society. 3D nanowire FET scaffold to record and stimulate cultured cells: Reproduced with permission. [102] Copyright 2016, Springer Nature. c) Tissue scale bioelectronics based on 1D nanomaterials for signal recording and therapeutic functions. Nanofiber-based cuff electrode for neuroprosthetics: Reproduced with permission. [116]

show abstract

“…Lv et al developed antibacterial mats based on AgNPsloaded starch/PEO nanofibers for medical care. The obtained NFs indicated limited antibacterial activity [34]. So far, studies have revealed that antibacterial agents other than N-halamine compounds have a considerable decrease in bactericidal activity, which is one of the technology's major drawbacks [35].…”

Section: Introductionmentioning

confidence: 99%

Production and Characterization of N-Halamine Based Polyvinyl Chloride (PVC) Nanowebs

Çobanoğlu¹,

Parın²,

Yildirim³

2021

Tekstil Ve Konfeksiyon

View full text Add to dashboard Cite

Antibacterial agent N-halamine, 7,7,9,9-tetramethyl-1,3,8-triazaspiro [4.5]-decane-2,4-dione (TTDD), was synthesized, and it was added into the polyvinyl chloride (PVC) nanoweb. A versatile, and relatively simple method, electrospinning, was used to fabricate continuous and uniform nanowebs. 7,7,9,9-tetramethyl-1,3,8-triazaspiro [4.5]-decane-2,4-dione (TTDD) is a cyclic N-halamine that can be chlorinated easily due to three functional groups (imide, amide, and amine). Therefore, TTDD was preferred for PVC regarding having high stability, non-toxic, non-irritant for skin, and renewable. The rechargeable chlorination process was applied to webs using dilute hypochlorite solution. The antibacterial activity of the webs were evaluated using the ASTM 2149 procedure. FTIR, TGA, and SEM were used to investigate the morphology, thermal characteristics, and chemical structures of PVC webs. Scanning electron microscopy (SEM) displayed that the average diameter of the fibers increased with TTDD concentration. The thermal properties of the PVC webs did not changed significantly. All chlorinated webs indicated highly effective antibacterial activities against both Staphylococcus aureus and Escherichia coli with increased inactivation. Furthermore, the antibacterial efficacy of nanowebs is reformed again by the rechargeable process. The rechargeable chlorination capacity of obtained PVC non-wovens is over > 60% (within 6 hours, in pH 5), for four rechargeable chlorine cycles. The new antibacterial PVC nanowebs have the potential for especially useful in medical applications.

show abstract

AgNPs-incorporated nanofiber mats: Relationship between AgNPs size/content, silver release, cytotoxicity, and antibacterial activity

Cited by 60 publications

References 51 publications

Antimicrobial Effect of Electrospun Nanofibers Loaded with Silver Nanoparticles: Influence of Ag Incorporation Method

Antimicrobial Effect of Electrospun Nanofibers Loaded with Silver Nanoparticles: Influence of Ag Incorporation Method

Recent Advances in 1D Nanomaterial‐Based Bioelectronics for Healthcare Applications

Production and Characterization of N-Halamine Based Polyvinyl Chloride (PVC) Nanowebs

Contact Info

Product

Resources

About