2009
DOI: 10.1016/j.clinbiochem.2009.07.027
|View full text |Cite|
|
Sign up to set email alerts
|

AgNORs count and DNA ploidy in liver biopsies from patients with schistosomal liver cirrhosis and hepatocellular carcinoma

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
8
0

Year Published

2011
2011
2021
2021

Publication Types

Select...
3
3

Relationship

0
6

Authors

Journals

citations
Cited by 8 publications
(8 citation statements)
references
References 28 publications
0
8
0
Order By: Relevance
“…Recently, we compared the results of DNA flow cytometry and AgNORs with the histopathological data. It was found that the lowest mean AgNOR count per nucleus was found in the normal liver (1.3± 0.9) and the highest count was (3.89± 0.827) in tumor lesion of HCC (Attallah et al, 2009b). A gradual increase in the AgNOR count per nucleus was noted as disease progressed from normal liver through liver cirrhosis to HCC tumor lesions.…”
Section: Agnor Count Reflects Dna Ploidy or Proliferative Activitymentioning
confidence: 74%
See 3 more Smart Citations
“…Recently, we compared the results of DNA flow cytometry and AgNORs with the histopathological data. It was found that the lowest mean AgNOR count per nucleus was found in the normal liver (1.3± 0.9) and the highest count was (3.89± 0.827) in tumor lesion of HCC (Attallah et al, 2009b). A gradual increase in the AgNOR count per nucleus was noted as disease progressed from normal liver through liver cirrhosis to HCC tumor lesions.…”
Section: Agnor Count Reflects Dna Ploidy or Proliferative Activitymentioning
confidence: 74%
“…Moreover, FCM can identify cases with high cell proliferation (high S phase and G2/M), which are very susceptible to different mutagenic agents or chemicals, which results in neoplastic transformation. FCM can therefore be considered as a better ancillary technique in the assessment of liver cell dysplasia because it is objective and not able to misinterpretation or inter-observer discordance (Attallah et al, 2009b). In our previous study (El-Sayed et al, 2004), liver cell dysplasia was found in 60 % of patients with liver cirrhosis, small cell dysplasia in 38 % and large cell dysplasia in 62 %.…”
Section: Dna Ploidy and Liver Cell Dysplasia In Liver Biopsies From Pmentioning
confidence: 99%
See 2 more Smart Citations
“…Previously, nucleolar staining by AgNORs was considered to be a prognostic marker of malignancy (25). Moreover, the value of AgNORs as proliferation markers has been reported in various forms of cancer, such as breast, ovarian, cervical, prostate, hepatocellular, papillary thyroid, gastric and bladder cancer (2531).…”
Section: Overexpression Of Eif6 In Human Carcinomamentioning
confidence: 99%