2015
DOI: 10.1111/pde.12563
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Agminated Flexural Melanocytic Nevi: A Late Sequela of Langerhans Cell Histiocytosis?

Abstract: Agminated flexural melanocytic nevi in children with a history of Langerhans cell histiocytosis (LCH) are rare and thought to be coincidental or related to systemic chemotherapy. We report on an 11-year-old boy in remission from LCH, treated with only topical steroids, who presented years later with an eruption of melanocytic nevi in the bilateral inguinal and axillary regions. Rather than coincidence, we hypothesize that agminated flexural melanocytic nevi are a late sequela of LCH, possibly resulting from im… Show more

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Cited by 6 publications
(12 citation statements)
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“…LCH skin involvement was described in 4 of 5 patients; however, all patients presented pigmented lesions in the folds, especially the groin and axillae. None of the patients developed naevi on the scalp, the area mostly involved in LCH (3)(4)(5).…”
Section: Discussionmentioning
confidence: 93%
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“…LCH skin involvement was described in 4 of 5 patients; however, all patients presented pigmented lesions in the folds, especially the groin and axillae. None of the patients developed naevi on the scalp, the area mostly involved in LCH (3)(4)(5).…”
Section: Discussionmentioning
confidence: 93%
“…One patient received only vinblastine (3). The case described by Feldstein et al (5) was treated with topical corticosteroids only. Our case received vinblastine, prednisone and methotrexate treatment (Table SI 1 ).…”
Section: Discussionmentioning
confidence: 99%
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